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BPMC

Blueprint Medicines
BPMC

Delisted

BPMC was delisted on the 17th of July, 2025.

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5 hedge funds and large institutions have $2.58M invested in Blueprint Medicines in 2025 Q3 according to their latest regulatory filings, with 0 funds opening new positions, 1 increasing their positions, 3 reducing their positions, and 344 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% less repeat investments, than reductions

Existing positions increased: 1 | Existing positions reduced: 3

99% less funds holding

Funds holding: 354 → 5 (-349)

99.54% less ownership

Funds ownership: 99.58% → 0.04% (-100%)

100% less capital invested

Capital invested by funds: $8.24B → $2.58M (-$8.24B)

100% less funds holding in top 10

Funds holding in top 10: 29 → 0 (-29)

100% less first-time investments, than exits

New positions opened: 0 | Existing positions closed: 344

Holders
5
Holders Change
-349
Holders Change %
-98.59%
% of All Funds
0.07%
Holding in Top 10
–
Holding in Top 10 Change
-29
Holding in Top 10 Change %
-100%
% of All Funds
–
New
–
Increased
1
Reduced
3
Closed
344
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
IA
IFP Advisors
Florida
+$2.06K

Top Sellers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
-$822M
2
BlackRock
BlackRock
New York
-$784M
3
PCM
Pentwater Capital Management
Florida
-$500M
4
State Street
State Street
Massachusetts
-$286M
5
UBS Group
UBS Group
Switzerland
-$278M
Name Holding Trade Value Shares
Change 		Change in
Stake
State of Wisconsin Investment Board
101
State of Wisconsin Investment Board
Wisconsin
– -$11.5M -89,373 Closed
VI
102
Versor Investments
New York
– -$11.3M -88,042 Closed
California Public Employees Retirement System
103
California Public Employees Retirement System
California
– -$11.1M -86,709 Closed
Prudential Financial
104
Prudential Financial
New Jersey
– -$10.8M -83,973 Closed
AA
105
AQR Arbitrage
Connecticut
– -$10.3M -80,179 Closed
ECM
106
Eisler Capital Management
United Kingdom
– -$10M -78,198 Closed
TD Asset Management
107
TD Asset Management
Ontario, Canada
– -$9.88M -77,100 Closed
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
108
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
– -$9.61M -75,000 Closed
Manulife (Manufacturers Life Insurance)
109
Manulife (Manufacturers Life Insurance)
Ontario, Canada
– -$9.58M -74,708 Closed
OAM
110
Oberweis Asset Management
Illinois
– -$9.29M -72,500 Closed
HF
111
HRT Financial
New York
– -$8.96M -69,916 Closed
Raymond James Financial
112
Raymond James Financial
Florida
– -$8.52M -66,461 Closed
Qube Research & Technologies (QRT)
113
Qube Research & Technologies (QRT)
United Kingdom
– -$8.5M -66,275 Closed
WCMNY
114
Westchester Capital Management (New York)
New York
– -$8.32M -64,928 Closed
JG
115
Jain Global
New York
– -$8.22M -64,130 Closed
California State Teachers Retirement System (CalSTRS)
116
California State Teachers Retirement System (CalSTRS)
California
– -$8.19M -63,898 Closed
HIM
117
Hillsdale Investment Management
Ontario, Canada
– -$8.08M -63,000 Closed
Rafferty Asset Management
118
Rafferty Asset Management
New York
– -$7.76M -60,567 Closed
Massachusetts Financial Services
119
Massachusetts Financial Services
Massachusetts
– -$7.74M -60,349 Closed
PCM
120
Prelude Capital Management
New York
– -$7.71M -60,154 Closed
AIMCA
121
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
– -$7.69M -60,000 Closed
CCM
122
Chicago Capital Management
Illinois
– -$7.69M -60,000 Closed
CL
123
CSS LLC
Illinois
– -$7.68M -59,886 Closed
Simplex Trading
124
Simplex Trading
Illinois
– -$7.18M -55,989 Closed
PAS
125
Point72 Asia (Singapore)
Singapore
– -$7.1M -55,365 Closed
3 4
5
6 7

BPMC Hedge Fund Activity: Q3 2025 in Review

5 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q3 2025, worth a combined $2.58M — down 100% from $8.24B a quarter earlier.

Sellers outnumbered buyers: 344 funds closed out of BPMC and 0 opened new positions — a net loss of 344 holders — while 3 trimmed existing stakes and 1 added.

The largest buyer was IFP Advisors, adding an estimated $2.06K. The largest seller was Vanguard Group, exiting entirely with an estimated $822M sold.

  • 5 institutional investors held Blueprint Medicines (BPMC) as of Q3 2025, down from 354 in Q2 2025.
  • Funds reported $2.58M of Blueprint Medicines stock for Q3 2025, down 100% quarter-over-quarter.
  • 0 funds opened new Blueprint Medicines positions in Q3 2025 and 344 closed out, a net change of -344 holders.
  • The largest Blueprint Medicines buyer in Q3 2025 was IFP Advisors, an estimated $2.06K added.
  • The largest Blueprint Medicines seller in Q3 2025 was Vanguard Group, an estimated $822M sold.

Based on aggregated 13F filings for Q3 2025.