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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
101
Tygh Capital Management
Oregon
$3.85M -$1.67K -16 -0%
State of New Jersey Common Pension Fund D
102
State of New Jersey Common Pension Fund D
New Jersey
$3.76M +$18.3K +175 +0.5%
SEI Investments
103
SEI Investments
Pennsylvania
$3.75M -$39.4K -377 -1%
Susquehanna International Group
104
Susquehanna International Group
Pennsylvania
$3.73M +$291K +2,784 +9%
RJFSA
105
Raymond James Financial Services Advisors
Florida
$3.6M +$624K +5,969 +22%
Allspring Global Investments
106
Allspring Global Investments
North Carolina
$3.44M +$3.35M +32,071 New
Millennium Management
107
Millennium Management
New York
$3.42M -$5.91M -56,517 -64%
AIG
108
American International Group
New York
$3.33M -$97.4K -931 -3%
Nomura Asset Management
109
Nomura Asset Management
Japan
$3.21M +$541K +5,172 +21%
NC
110
NBW Capital
Massachusetts
$3.19M +$270K +2,578 +9%
Toronto Dominion Bank
111
Toronto Dominion Bank
Ontario, Canada
$3.12M +$3.04M +29,100 New
SGI
112
Summit Global Investments
Utah
$3.03M +$440K +4,202 +17%
EAM
113
Erste Asset Management
Austria
$3.02M
PIM
114
Platinum Investment Management
Australia
$2.9M
ORI
115
Oak Ridge Investments
Illinois
$2.88M -$46.5K -445 -2%
RJA
116
Raymond James & Associates
Florida
$2.85M +$682K +6,520 +32%
BG
117
Bellevue Group
Switzerland
$2.73M +$2.67M +25,500 New
GTCM
118
Gyon Technologies Capital Management
New Jersey
$2.64M +$434K +4,147 +20%
DekaBank Deutsche Girozentrale
119
DekaBank Deutsche Girozentrale
Germany
$2.58M +$62.8K +600 +3%
State Board of Administration of Florida Retirement System
120
State Board of Administration of Florida Retirement System
Florida
$2.5M -$49.8K -476 -2%
Bank of Montreal
121
Bank of Montreal
Ontario, Canada
$2.44M +$2.3M +22,008 New
ProShare Advisors
122
ProShare Advisors
Maryland
$2.42M +$120K +1,143 +5%
SF
123
Synovus Financial
Georgia
$2.29M +$22.9K +219 +1%
MIM
124
MetLife Investment Management
New Jersey
$2.21M
AQR Capital Management
125
AQR Capital Management
Connecticut
$2.15M -$1.07M -10,232 -34%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.