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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Comerica Bank
76
Comerica Bank
Texas
$7.08M -$195K -1,860 -2%
SAM
77
Sectoral Asset Management
Quebec, Canada
$7.05M +$6.88M +65,800 New
Wells Fargo
78
Wells Fargo
California
$6.95M -$1.91M -18,248 -22%
UBS Group
79
UBS Group
Switzerland
$6.89M +$1.22M +11,617 +22%
Citigroup
80
Citigroup
New York
$6.76M +$424K +4,056 +7%
RhumbLine Advisers
81
RhumbLine Advisers
Massachusetts
$6.7M -$141K -1,347 -2%
WP
82
Woodline Partners
California
$6.65M -$11.5M -109,980 -64%
SBH
83
Segall Bryant & Hamill
Illinois
$6.3M +$1.62M +15,498 +36%
Assenagon Asset Management
84
Assenagon Asset Management
Luxembourg
$6.25M -$19.6M -187,818 -76%
Rafferty Asset Management
85
Rafferty Asset Management
New York
$5.83M +$2.39M +22,836 +72%
First Trust Advisors
86
First Trust Advisors
Illinois
$5.8M +$4.32M +41,306 +323%
Legal & General Group
87
Legal & General Group
United Kingdom
$5.67M +$68.6K +656 +1%
CS
88
Credit Suisse
Switzerland
$5.63M -$96.5K -923 -2%
GIM
89
Granahan Investment Management
Massachusetts
$5.43M -$217K -2,072 -4%
Ameriprise
90
Ameriprise
Minnesota
$5.32M +$293K +2,805 +6%
New York State Common Retirement Fund
91
New York State Common Retirement Fund
New York
$5.19M -$23.6K -226 -0.5%
Russell Investments Group
92
Russell Investments Group
United Kingdom
$4.76M -$1.12M -10,664 -19%
Man Group
93
Man Group
United Kingdom
$4.58M -$1.8M -17,238 -29%
MOACM
94
Mutual of America Capital Management
New York
$4.54M -$41.3K -395 -0.9%
Balyasny Asset Management
95
Balyasny Asset Management
Illinois
$4.5M +$1.52M +14,531 +53%
GC
96
Guggenheim Capital
Illinois
$4.27M -$669K -6,398 -14%
CAM
97
ClariVest Asset Management
California
$4.18M -$1.56M -14,925 -28%
MCM
98
Moore Capital Management
New York
$4.14M -$13.2M -126,415 -77%
SG Americas Securities
99
SG Americas Securities
New York
$3.88M +$1.26M +12,052 +50%
Nordea Investment Management
100
Nordea Investment Management
Sweden
$3.87M -$50.5K -483 -1%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.