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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
NHAS
51
Novo Holdings A/S
Denmark
$21.1M
EHI
52
Eagle Health Investments
Connecticut
$20.6M +$1.72M +16,464 +9%
D.E. Shaw & Co
53
D.E. Shaw & Co
New York
$19.3M -$2.86M -27,382 -13%
PAM
54
Panagora Asset Management
Massachusetts
$18.9M +$3.31M +31,654 +22%
EA
55
Emerald Advisers
Pennsylvania
$18.2M -$6.68M -63,849 -27%
Morgan Stanley
56
Morgan Stanley
New York
$14.9M +$449K +4,294 +3%
California Public Employees Retirement System
57
California Public Employees Retirement System
California
$13.9M
PCM
58
Peregrine Capital Management
Minnesota
$13.2M +$366K +3,500 +3%
Swiss National Bank
59
Swiss National Bank
Switzerland
$13.1M
EAM
60
EFG Asset Management
Oregon
$12.1M +$11.8M +112,715 New
Prudential Financial
61
Prudential Financial
New Jersey
$11.9M +$283K +2,706 +3%
DM
62
Deerfield Management
New York
$11.8M -$7.88M -75,354 -41%
TD Asset Management
63
TD Asset Management
Ontario, Canada
$11.3M +$2.42M +23,164 +28%
B
64
Bailard
California
$10.5M -$107K -1,023 -1%
Invesco
65
Invesco
Georgia
$10.4M -$4.72M -45,126 -32%
Citadel Advisors
66
Citadel Advisors
Florida
$10.3M +$9.7M +92,741 +2,596%
Axa
67
Axa
France
$9.59M -$2.17M -20,700 -19%
Allianz Asset Management
68
Allianz Asset Management
Germany
$9.15M -$940K -8,988 -10%
California State Teachers Retirement System (CalSTRS)
69
California State Teachers Retirement System (CalSTRS)
California
$8.46M +$204K +1,953 +3%
State of Wisconsin Investment Board
70
State of Wisconsin Investment Board
Wisconsin
$8.39M +$397K +3,800 +5%
IHAM
71
Integral Health Asset Management
New York
$8.03M -$2.41M -23,000 -23%
Barclays
72
Barclays
United Kingdom
$7.77M +$2.98M +28,481 +65%
VOYA Investment Management
73
VOYA Investment Management
Georgia
$7.72M -$8.65M -82,687 -53%
PPA
74
Parametric Portfolio Associates
Washington
$7.52M +$912K +8,720 +14%
Ensign Peak Advisors
75
Ensign Peak Advisors
Utah
$7.26M +$2.13M +20,368 +43%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.