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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$68.9M -$4.56M -43,629 -6%
Lord, Abbett & Co
27
Lord, Abbett & Co
New Jersey
$60.2M +$14.4M +137,882 +32%
BC
28
Boxer Capital
California
$54.3M +$8.62M +82,374 +19%
Dimensional Fund Advisors
29
Dimensional Fund Advisors
Texas
$48.9M +$18.4M +175,896 +63%
CCM
30
Cadian Capital Management
New York
$48.3M -$62.9M -601,546 -57%
Charles Schwab
31
Charles Schwab
California
$46.9M -$2.89M -27,614 -6%
Franklin Resources
32
Franklin Resources
California
$45.1M -$7.49M -71,641 -15%
Goldman Sachs
33
Goldman Sachs
New York
$42.9M -$22.2M -212,594 -35%
Fisher Asset Management
34
Fisher Asset Management
Washington
$42.9M +$8.85M +84,615 +27%
Victory Capital Management
35
Victory Capital Management
Texas
$42.9M +$41.1M +393,124 +5,523%
EAM
36
Eventide Asset Management
Massachusetts
$42.4M +$4.16M +39,800 +11%
EAM
37
Eagle Asset Management
Florida
$42.1M -$1.32M -12,602 -3%
Loomis, Sayles & Company
38
Loomis, Sayles & Company
Massachusetts
$40.6M -$1.07M -10,229 -3%
N
39
Nuveen
North Carolina
$39.1M +$495K +4,737 +1%
CS
40
Candriam SCA
Luxembourg
$37.7M +$4.11M +39,293 +13%
DCM
41
Driehaus Capital Management
Illinois
$33.8M +$14.7M +140,480 +80%
First Manhattan
42
First Manhattan
New York
$33.8M -$228K -2,175 -0.7%
Bank of America
43
Bank of America
North Carolina
$30.6M +$2.56M +24,448 +9%
EVM
44
Eaton Vance Management
Massachusetts
$28.2M -$29K -277 -0.1%
Jennison Associates
45
Jennison Associates
New York
$26.9M -$15.2M -144,893 -37%
SI
46
Sofinnova Investments
California
$26.3M +$6.62M +63,322 +35%
UBS AM
47
UBS AM
Illinois
$25.1M -$2.77M -26,474 -10%
EMFAT
48
Emerald Mutual Fund Advisers Trust
Pennsylvania
$23.8M -$2.44M -23,340 -10%
DCM
49
DAFNA Capital Management
California
$22.2M
Deutsche Bank
50
Deutsche Bank
Germany
$21.6M -$23.7M -226,543 -53%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.