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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
MPWT
276
MassMutual Private Wealth & Trust
Connecticut
$1K +$628 +6 New
SC
277
Schubert & Co
Texas
$1K +$941 +9 New
JWA
278
JFS Wealth Advisors
Pennsylvania
$1K +$1.46K +14 New
Point72 Asset Management
279
Point72 Asset Management
Connecticut
-$43M -418,200 Closed
CAM
280
Cormorant Asset Management
Massachusetts
-$15.4M -150,000 Closed
Mirae Asset Global Investments
281
Mirae Asset Global Investments
South Korea
-$12.7M -123,042 Closed
AG
282
Artal Group
Luxembourg
-$10.3M -100,000 Closed
SL
283
SIB LLC
New York
-$6.7M -65,151 Closed
CM
284
Caption Management
Oklahoma
-$2.54M -24,291 Closed
SSA
285
Schonfeld Strategic Advisors
New York
-$2.04M -19,818 Closed
Hudson Bay Capital Management
286
Hudson Bay Capital Management
Connecticut
-$1.28M -12,500 Closed
Lazard Asset Management
287
Lazard Asset Management
New York
-$1.16M -11,277 Closed
AIL
288
AGF Investments LLC
Ontario, Canada
-$683K -6,640 Closed
ESCM
289
Echo Street Capital Management
New York
-$658K -6,403 Closed
HSA
290
Hussman Strategic Advisors
Maryland
-$637K -6,200 Closed
Bank of Nova Scotia
291
Bank of Nova Scotia
Ontario, Canada
-$563K -5,473 Closed
DF
292
Donoghue Forlines
Massachusetts
-$529K -5,142 Closed
MGIM
293
M&G Investment Management
United Kingdom
-$509 -4,937 Closed
GCP
294
GSA Capital Partners
United Kingdom
-$505K -4,908 Closed
SEC
295
Seven Eight Capital
New York
-$500K -4,860 Closed
HSBC Holdings
296
HSBC Holdings
United Kingdom
-$382K -3,701 Closed
New York State Teachers Retirement System (NYSTRS)
297
New York State Teachers Retirement System (NYSTRS)
New York
-$329K -3,200 Closed
HF
298
HRT Financial
New York
-$317K -3,090 Closed
MCM
299
Marathon Capital Management
Maryland
-$292K -2,839 Closed
CIM
300
CIM Investment Management
Pennsylvania
-$290K -2,825 Closed

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.