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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
KTC
251
Kistler-Tiffany Companies
Pennsylvania
$11K
Northwestern Mutual Wealth Management
252
Northwestern Mutual Wealth Management
Wisconsin
$11K
IA
253
IFP Advisors
Florida
$11K +$941 +9 +10%
S
254
SignatureFD
Georgia
$11K +$1.78K +17 +19%
ACM
255
Anfield Capital Management
California
$11K +$10.3K +98 +1,225%
SWM
256
Spire Wealth Management
Virginia
$9K
EWA
257
EverSource Wealth Advisors
Alabama
$9K +$8.47K +81 New
LPWM
258
Lake Point Wealth Management
Texas
$8K
SGAM
259
Smith Group Asset Management
Texas
$7K
DFCM
260
Dark Forest Capital Management
Puerto Rico
$6K -$217K -2,078 -98%
TC
261
Truvestments Capital
Florida
$5K -$2.2K -21 -29%
Manulife (Manufacturers Life Insurance)
262
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.2K -$33K -315 -1%
CWP
263
Concord Wealth Partners
Virginia
$3K
RA
264
Resolute Advisors
California
$3K
PFGIA
265
Patriot Financial Group Insurance Agency
Massachusetts
$3K +$2.62K +25 +357%
WTA
266
Washington Trust Advisors
Massachusetts
$3K +$3.24K +31 New
VRS
267
Virginia Retirement Systems
Virginia
$1.63K -$1.19M -11,400 -43%
APA
268
American Portfolios Advisors
New York
$1.07K
QCG
269
Quadrant Capital Group
Ohio
$1K -$2.72K -26 -65%
BAM
270
Bellevue Asset Management
Washington
$1K -$105 -1 -7%
AAP
271
Arax Advisory Partners
Colorado
$1K
GWS
272
Glassman Wealth Services
Virginia
$1K
GWSG
273
GPS Wealth Strategies Group
Colorado
$1K
IFAM
274
Institutional & Family Asset Management
Colorado
$1K
TFO
275
Tarbox Family Office
California
$1K

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.