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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
SOW
226
State of Wyoming
Wyoming
$54K -$23.4K -224 -31%
LSA
227
Leonteq Securities AG
Switzerland
$51.1K +$20.9K +200 +72%
C
228
Covestor
United Kingdom
$46K +$45K +430 New
PCG
229
Private Capital Group
Connecticut
$45K -$19.2K -184 -30%
Federated Hermes
230
Federated Hermes
Pennsylvania
$42K -$2.72K -26 -6%
ED
231
Exane Derivatives
France
$41.7K +$37.9K +362 +1,341%
Baillie Gifford & Co
232
Baillie Gifford & Co
United Kingdom
$34K -$2.93K -28 -8%
Carson Wealth (CWM LLC)
233
Carson Wealth (CWM LLC)
Nebraska
$34K +$33.5K +320 New
FF
234
FourThought Financial
Florida
$33K
PCH
235
Polar Capital Holdings
United Kingdom
$26.8K +$15.7M +150,000 +150%
Rockefeller Capital Management
236
Rockefeller Capital Management
New York
$25K -$27.8K -266 -53%
RFWA
237
RPg Family Wealth Advisory
Massachusetts
$22.2K
HI
238
Harbour Investments
Wisconsin
$21K -$2.82K -27 -12%
MCM
239
Manchester Capital Management
Vermont
$20K
FMII
240
Farmers & Merchants Investments Inc
Nebraska
$19K -$4.29K -41 -19%
MIM
241
Macroview Investment Management
Maryland
$19K +$18.5K +177 New
UB
242
UMB Bank
Missouri
$19K +$18.7K +179 New
Daiwa Securities Group
243
Daiwa Securities Group
Japan
$18K -$3.03K -29 -14%
HNB
244
Huntington National Bank
Ohio
$17K -$9.31K -89 -35%
PA
245
Parallel Advisors
California
$16K -$209 -2 -1%
CTC
246
Central Trust Company
Missouri
$16K
FFA
247
Freedman Financial Associates
Massachusetts
$16K
FHA
248
First Horizon Advisors
Tennessee
$14K -$1.46K -14 -9%
SPIA
249
Steward Partners Investment Advisory
New York
$13K
TWA
250
TCI Wealth Advisors
Arizona
$12K

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.