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Axsome Therapeutics
AXSM

Overview Fund Activity

349 hedge funds and large institutions have $4.32B invested in Axsome Therapeutics in 2025 Q1 according to their latest regulatory filings, with 91 funds opening new positions, 101 increasing their positions, 114 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
349
Holders Change
+59
Holders Change %
+20.34%
% of All Funds
4.74%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.16%
New
91
Increased
101
Reduced
114
Closed
29
Calls
$111M
Puts
$86.5M
Net Calls
+$24.5M
Net Calls Change
-$35M

Top Buyers

1
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
$73.2M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
$63.9M
3
O
OrbiMed
New York
$45.1M
4
1832 Asset Management
1832 Asset Management
Ontario, Canada
$42.4M
5
Man Group
Man Group
United Kingdom
$59.9M

Top Sellers

1
RI
RTW Investments
New York
$341M
2
RCM
RA Capital Management
Massachusetts
$0
3
FFM
Fairmount Funds Management
Pennsylvania
$95.1M
4
Lazard Asset Management
Lazard Asset Management
New York
$3.41M
5
HRCM
Hood River Capital Management
Florida
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Pictet Asset Management
26
Pictet Asset Management
Switzerland
$38.9M +$38.3M +328,527 +7,023%
WP
27
Woodline Partners
California
$35.5M -$12.2M -104,357 -26%
Goldman Sachs
28
Goldman Sachs
New York
$35.2M +$9.81M +84,151 +39%
Principal Financial Group
29
Principal Financial Group
Iowa
$34.5M +$10.3M +88,606 +43%
UBS Group
30
UBS Group
Switzerland
$33.7M +$16.5M +141,300 +96%
NNPTE
31
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$33.3M +$29.4M +251,775 +747%
Loomis, Sayles & Company
32
Loomis, Sayles & Company
Massachusetts
$33.1M -$693K -5,941 -2%
Qube Research & Technologies (QRT)
33
Qube Research & Technologies (QRT)
United Kingdom
$32.9M +$14.7M +126,465 +81%
T. Rowe Price Investment Management
34
T. Rowe Price Investment Management
Maryland
$31.1M +$31.1M +266,997 New
CAM
35
Cormorant Asset Management
Massachusetts
$29.2M -$8.75M -75,000 -23%
Voloridge Investment Management
36
Voloridge Investment Management
Florida
$27.5M +$27.5M +235,383 New
Millennium Management
37
Millennium Management
New York
$27.4M +$26.9M +231,065 +5,442%
Franklin Resources
38
Franklin Resources
California
$26.4M +$5.16M +44,225 +24%
DCM
39
Driehaus Capital Management
Illinois
$25M +$25M +214,139 New
BNP Paribas Financial Markets
40
BNP Paribas Financial Markets
France
$21.3M -$353K -3,029 -2%
MIM
41
MetLife Investment Management
New Jersey
$20.9M +$18.3M +156,678 +703%
CSS
42
Cubist Systematic Strategies
Connecticut
$20.7M +$7.1M +60,877 +52%
Connor, Clark & Lunn Investment Management (CC&L)
43
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$20.5M +$11.9M +102,445 +139%
SI
44
Sofinnova Investments
California
$20.4M -$36.9M -316,409 -64%
Raymond James Financial
45
Raymond James Financial
Florida
$18.1M -$2.28M -19,511 -11%
Two Sigma Advisers
46
Two Sigma Advisers
New York
$17.4M +$16.7M +143,300 +2,275%
Squarepoint
47
Squarepoint
New York
$16.5M +$6.08M +52,167 +58%
GIP
48
Granite Investment Partners
California
$16.2M +$5.49M +47,070 +51%
Renaissance Technologies
49
Renaissance Technologies
New York
$15.7M +$15.7M +134,400 New
Bank of New York Mellon
50
Bank of New York Mellon
New York
$15.3M -$411K -3,527 -3%
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