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Axsome Therapeutics
AXSM

Overview Fund Activity

341 hedge funds and large institutions have $3.95B invested in Axsome Therapeutics in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 151 increasing their positions, 89 reducing their positions, and 57 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
341
Holders Change
-8
Holders Change %
-2.29%
% of All Funds
4.57%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
54
Increased
151
Reduced
89
Closed
57
Calls
$66.7M
Puts
$69.3M
Net Calls
-$2.59M
Net Calls Change
-$27.1M

Top Buyers

1
DTC
Deep Track Capital
Connecticut
$83.7M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$64M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$46.7M
4
HRCM
Hood River Capital Management
Florida
$38.7M
5
BlackRock
BlackRock
New York
$400M

Top Sellers

1
RI
RTW Investments
New York
$158M
2
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
$18.9M
3
1832 Asset Management
1832 Asset Management
Ontario, Canada
$0
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
$21M
5
Invesco
Invesco
Georgia
$59.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
Vanguard Group
1
Vanguard Group
Pennsylvania
$412M +$7.11M +68,078 +2%
BlackRock
2
BlackRock
New York
$400M +$32.4M +310,579 +9%
BI
3
BVF Inc
California
$176M – – –
RI
4
RTW Investments
New York
$158M -$147M -1,405,826 -48%
Macquarie Group
5
Macquarie Group
Australia
$119M +$16.9M +161,488 +17%
Geode Capital Management
6
Geode Capital Management
Massachusetts
$103M +$5.7M +54,600 +6%
Fidelity Investments
7
Fidelity Investments
Massachusetts
$102M -$28.2M -270,501 -22%
State Street
8
State Street
Massachusetts
$100M +$5.48M +52,483 +6%
FFM
9
Fairmount Funds Management
Pennsylvania
$85.1M – – –
DTC
10
Deep Track Capital
Connecticut
$83.7M +$83.7M +801,371 New
Bank of America
11
Bank of America
North Carolina
$78.7M +$22.9M +219,527 +41%
EAM
12
Eventide Asset Management
Massachusetts
$75.7M -$2M -19,178 -3%
Wellington Management Group
13
Wellington Management Group
Massachusetts
$75.7M +$2.27M +21,765 +3%
ACM
14
Alethea Capital Management
Washington
$69.7M – – –
T. Rowe Price Associates
15
T. Rowe Price Associates
Maryland
$64M +$60.6M +580,766 +1,816%
UBS Group
16
UBS Group
Switzerland
$62.2M +$32M +306,808 +106%
Invesco
17
Invesco
Georgia
$59.7M -$29.8M -285,452 -33%
Man Group
18
Man Group
United Kingdom
$54.8M +$1.24M +11,848 +2%
PHS
19
PFM Health Sciences
California
$50.4M -$7.67M -73,440 -13%
Norges Bank
20
Norges Bank
Norway
$48.9M +$48.9M +468,329 New
Morgan Stanley
21
Morgan Stanley
New York
$46.8M -$991K -9,497 -2%
Adage Capital Partners
22
Adage Capital Partners
Massachusetts
$46.7M +$41.7M +399,000 +831%
O
23
OrbiMed
New York
$44.7M +$4.3M +41,200 +11%
Pictet Asset Management
24
Pictet Asset Management
Switzerland
$43M +$8.21M +78,645 +24%
Northern Trust
25
Northern Trust
Illinois
$42.7M -$164K -1,575 -0.4%
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