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Axsome Therapeutics
AXSM

Overview Fund Activity

349 hedge funds and large institutions have $4.32B invested in Axsome Therapeutics in 2025 Q1 according to their latest regulatory filings, with 91 funds opening new positions, 101 increasing their positions, 114 reducing their positions, and 29 closing their positions.

Holders
349
Holders Change
+59
Holders Change %
+20.34%
% of All Funds
4.74%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.16%
New
91
Increased
101
Reduced
114
Closed
29
Calls
$111M
Puts
$86.5M
Net Calls
+$24.5M
Net Calls Change
-$35M

Top Buyers

1
Assenagon Asset Management
1
Assenagon Asset Management
Luxembourg
$73.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$63.9M
3
NL
3
Nuveen LLC
North Carolina
$48.2M
4
O
4
OrbiMed
New York
$45.1M
5
1832 Asset Management
5
1832 Asset Management
Ontario, Canada
$42.4M

Top Sellers

1
RI
1
RTW Investments
New York
$341M
2
RCM
2
RA Capital Management
Massachusetts
$0
3
FFM
3
Fairmount Funds Management
Pennsylvania
$95.1M
4
Lazard Asset Management
4
Lazard Asset Management
New York
$3.41M
5
HRCM
5
Hood River Capital Management
Florida
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Vanguard Group
1
Vanguard Group
Pennsylvania
$452M 3,876,942 -25,537 -0.7%
BlackRock
2
BlackRock
New York
$411M 3,524,411 -8,983 -0.3%
RI
3
RTW Investments
New York
$341M 2,922,729 -1,128,636 -28%
BI
4
BVF Inc
California
$197M 1,690,221 +302,157 +22%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$145M 1,247,231 +246,785 +25%
Macquarie Group
6
Macquarie Group
Australia
$114M 976,260 +12,213 +1%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$109M 934,853 +22,315 +2%
State Street
8
State Street
Massachusetts
$106M 906,020 -41,231 -4%
Invesco
9
Invesco
Georgia
$100M 857,001 +164,537 +24%
FFM
10
Fairmount Funds Management
Pennsylvania
$95.1M 815,176 -653,807 -45%
EAM
11
Eventide Asset Management
Massachusetts
$86.9M 744,850 -83,861 -10%
Wellington Management Group
12
Wellington Management Group
Massachusetts
$82M 703,279 +30,122 +4%
ACM
13
Alethea Capital Management
Washington
$77.8M 667,368 -66,949 -9%
Assenagon Asset Management
14
Assenagon Asset Management
Luxembourg
$73.2M 627,418 +623,717 +16,853%
PHS
15
PFM Health Sciences
California
$64.9M 556,545 +89,118 +19%
D.E. Shaw & Co
16
D.E. Shaw & Co
New York
$63.9M 547,665 +527,319 +2,592%
Bank of America
17
Bank of America
North Carolina
$62.3M 533,902 +329,315 +161%
Man Group
18
Man Group
United Kingdom
$59.9M 513,221 +349,833 +214%
Morgan Stanley
19
Morgan Stanley
New York
$53.3M 457,416 -119,442 -21%
NL
20
Nuveen LLC
North Carolina
$48.2M 413,141 +413,141 New
Northern Trust
21
Northern Trust
Illinois
$47.9M 410,969 +8,469 +2%
O
22
OrbiMed
New York
$45.1M 386,700 +386,700 New
1832 Asset Management
23
1832 Asset Management
Ontario, Canada
$42.4M 363,200 +363,200 New
PA
24
Perceptive Advisors
New York
$41.4M 355,107 -308,967 -47%
Charles Schwab
25
Charles Schwab
California
$39.3M 337,246 +9,212 +3%
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