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Axsome Therapeutics

352 hedge funds and large institutions have $4.37B invested in Axsome Therapeutics in 2025 Q1 according to their latest regulatory filings, with 90 funds opening new positions, 104 increasing their positions, 115 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

221% more first-time investments, than exits

New positions opened: 90 | Existing positions closed: 28

39% more capital invested

Capital invested by funds: $3.15B → $4.37B (+$1.22B)

28% more call options, than puts

Call options by funds: $111M | Put options by funds: $86.5M

21% more funds holding

Funds holding: 292352 (+60)

9% more funds holding in top 10

Funds holding in top 10: 1112 (+1)

0.05% more ownership

Funds ownership: 76.73%76.78% (+0.05%)

10% less repeat investments, than reductions

Existing positions increased: 104 | Existing positions reduced: 115

Holders
352
Holders Change
+60
Holders Change %
+20.55%
% of All Funds
4.72%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.16%
New
90
Increased
104
Reduced
115
Closed
28
Calls
$111M
Puts
$86.5M
Net Calls
+$24.5M
Net Calls Change
-$35M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$452M -$2.91M -25,537 -0.7%
BlackRock
2
BlackRock
New York
$411M -$1.02M -8,983 -0.3%
RI
3
RTW Investments
New York
$341M -$129M -1,128,636 -28%
BI
4
BVF Inc
California
$197M +$34.4M +302,157 +22%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$145M +$28.1M +246,785 +25%
Macquarie Group
6
Macquarie Group
Australia
$114M +$1.39M +12,213 +1%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$109M +$2.54M +22,315 +2%
State Street
8
State Street
Massachusetts
$106M -$4.7M -41,231 -4%
Invesco
9
Invesco
Georgia
$100M +$18.7M +164,537 +24%
FFM
10
Fairmount Funds Management
Pennsylvania
$95.1M -$74.5M -653,807 -45%
EAM
11
Eventide Asset Management
Massachusetts
$86.9M -$9.55M -83,861 -10%
Wellington Management Group
12
Wellington Management Group
Massachusetts
$82M +$3.43M +30,122 +4%
ACM
13
Alethea Capital Management
Washington
$77.8M -$7.63M -66,949 -9%
Assenagon Asset Management
14
Assenagon Asset Management
Luxembourg
$73.2M +$71.1M +623,717 +16,853%
PHS
15
PFM Health Sciences
California
$64.9M +$10.2M +89,118 +19%
D.E. Shaw & Co
16
D.E. Shaw & Co
New York
$63.9M +$60.1M +527,319 +2,592%
Bank of America
17
Bank of America
North Carolina
$62.3M +$37.5M +329,315 +161%
Man Group
18
Man Group
United Kingdom
$59.9M +$39.9M +349,833 +214%
Morgan Stanley
19
Morgan Stanley
New York
$53.3M -$13.6M -119,442 -21%
Norges Bank
20
Norges Bank
Norway
$51M +$3.93M +34,471 +9%
N
21
Nuveen
North Carolina
$48.2M +$21.9M +191,939 +87%
Northern Trust
22
Northern Trust
Illinois
$47.9M +$965K +8,469 +2%
O
23
OrbiMed
New York
$45.1M +$44.1M +386,700 New
1832 Asset Management
24
1832 Asset Management
Ontario, Canada
$42.4M +$41.4M +363,200 New
PA
25
Perceptive Advisors
New York
$41.4M -$35.2M -308,967 -47%