Two Sigma Advisers
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Two Sigma Advisers’s Axsome Therapeutics AXSM Stock Holding History

Two Sigma Advisers’s Portfolio AXSM Stock Details AXSM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-188,500
Closed -$34.4M – 225
2025
Q4 		$34.4M Buy
+188,500
New +$26.3M 0.07% 236
2025
Q2 		– Sell
-149,600
Closed -$17.4M – 2324
2025
Q1 		$17.4M Buy
149,600
+143,300
+2,275% +$16.3M 0.04% 364
2024
Q4 		$533K Buy
6,300
+2,900
+85% +$267K ﹤0.01% 1750
2024
Q3 		$306K Buy
+3,400
New +$297K ﹤0.01% 1902
2022
Q2 		– Sell
-37,800
Closed -$1.56M – 2656
2022
Q1 		$1.56M Buy
37,800
+6,500
+21% +$201K ﹤0.01% 1391
2021
Q4 		$1.18M Sell
31,300
-2,800
-8% -$103K ﹤0.01% 1475
2021
Q3 		$1.12M Sell
34,100
-14,400
-30% -$561K ﹤0.01% 1557
2021
Q2 		$3.27M Sell
48,500
-81,200
-63% -$4.87M 0.01% 1064
2021
Q1 		$7.34M Buy
129,700
+48,400
+60% +$3.4M 0.02% 693
2020
Q4 		$6.62M Sell
81,300
-26,600
-25% -$1.99M 0.02% 718
2020
Q3 		$7.69M Sell
107,900
-12,900
-11% -$1.01M 0.02% 613
2020
Q2 		$9.94M Buy
120,800
+2,700
+2% +$208K 0.03% 555
2020
Q1 		$6.95M Buy
118,100
+91,400
+342% +$7.45M 0.03% 605
2019
Q4 		$2.76M Buy
+26,700
New +$1.08M 0.01% 1077

Other funds holding AXSM

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
DTC
Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Two Sigma Advisers's AXSM Position: Q1 2026 in Review

Two Sigma Advisers sold out of Axsome Therapeutics (AXSM) in Q1 2026, closing a stake of 188,500 shares — an estimated $34.4M sold.

Two Sigma Advisers first reported a position in AXSM in Q4 2019 and held it in 14 quarters. The position peaked at $34.4M in Q4 2025. 409 funds tracked by Wall St. Rank hold AXSM as of Q1 2026.

  • Two Sigma Advisers reported no remaining Axsome Therapeutics position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 188,500 Axsome Therapeutics shares in Q1 2026, an estimated $34.4M.
  • Two Sigma Advisers first reported a position in Axsome Therapeutics in Q4 2019 and held it in 14 quarters.
  • Two Sigma Advisers's Axsome Therapeutics position peaked at $34.4M in Q4 2025.
  • 409 funds tracked by Wall St. Rank held Axsome Therapeutics as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.