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Axsome Therapeutics
AXSM

Overview Fund Activity

338 hedge funds and large institutions have $3.93B invested in Axsome Therapeutics in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 149 increasing their positions, 88 reducing their positions, and 57 closing their positions.

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
4.54%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
54
Increased
149
Reduced
88
Closed
57
Calls
$48.1M
Puts
$38.8M
Net Calls
+$9.3M
Net Calls Change
-$15.2M

Top Buyers

1
DTC
1
Deep Track Capital
Connecticut
$83.7M
2
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$64M
3
Norges Bank
3
Norges Bank
Norway
$48.9M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$46.7M
5
HRCM
5
Hood River Capital Management
Florida
$38.7M

Top Sellers

1
RI
1
RTW Investments
New York
$158M
2
Assenagon Asset Management
2
Assenagon Asset Management
Luxembourg
$18.9M
3
1832 Asset Management
3
1832 Asset Management
Ontario, Canada
$0
4
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$21M
5
Invesco
5
Invesco
Georgia
$59.7M
Name Market Value Shares Shares
Change 		Shares
Change %
Qube Research & Technologies (QRT)
26
Qube Research & Technologies (QRT)
United Kingdom
$40.9M 391,617 +109,241 +39%
HRCM
27
Hood River Capital Management
Florida
$38.7M 371,104 +371,104 New
Charles Schwab
28
Charles Schwab
California
$37.2M 356,651 +19,405 +6%
Principal Financial Group
29
Principal Financial Group
Iowa
$37.1M 355,511 +59,840 +20%
Point72 Asset Management
30
Point72 Asset Management
Connecticut
$36.6M 350,973 +224,780 +178%
WP
31
Woodline Partners
California
$34.6M 331,131 +27,047 +9%
NNPTE
32
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$34.1M 326,318 +40,824 +14%
NL
33
Nuveen LLC
North Carolina
$29.5M 282,971 -130,170 -32%
Franklin Resources
34
Franklin Resources
California
$29.1M 278,510 +51,995 +23%
Loomis, Sayles & Company
35
Loomis, Sayles & Company
Massachusetts
$29M 277,465 -6,705 -2%
T. Rowe Price Investment Management
36
T. Rowe Price Investment Management
Maryland
$26M 248,726 -18,271 -7%
Goldman Sachs
37
Goldman Sachs
New York
$23.8M 228,204 -73,514 -24%
Connor, Clark & Lunn Investment Management (CC&L)
38
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$23.5M 224,721 +48,779 +28%
DCM
39
Driehaus Capital Management
Illinois
$23.3M 223,280 +9,141 +4%
Bank of New York Mellon
40
Bank of New York Mellon
New York
$21.3M 203,632 +72,609 +55%
D.E. Shaw & Co
41
D.E. Shaw & Co
New York
$21M 200,764 -346,901 -63%
PA
42
Perceptive Advisors
New York
$20.7M 198,534 -156,573 -44%
JPMorgan Chase & Co
43
JPMorgan Chase & Co
New York
$19.6M 187,728 +62,945 +50%
BNP Paribas Financial Markets
44
BNP Paribas Financial Markets
France
$19.5M 186,437 +3,805 +2%
MIM
45
MetLife Investment Management
New Jersey
$19.2M 184,164 +5,209 +3%
Assenagon Asset Management
46
Assenagon Asset Management
Luxembourg
$18.9M 180,960 -446,458 -71%
Squarepoint
47
Squarepoint
New York
$17M 163,000 +21,403 +15%
Raymond James Financial
48
Raymond James Financial
Florida
$16.8M 161,412 +6,337 +4%
CSS
49
Cubist Systematic Strategies
Connecticut
$16.6M 159,233 -18,581 -10%
TLP
50
Tri Locum Partners
New York
$16.5M 157,861 +56,621 +56%
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