|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$827M
|
+$300M
|
+2,509,034
|
+54%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$540M
|
-$120
|
-1
|
-0%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$476M
|
–
|
–
|
–
|
|
|
4
|
|
$443M
|
-$14.8M
|
-124,000
|
-3%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$390M
|
–
|
–
|
–
|
|
|
6
|
Vivo Capital
Palo Alto,
California
|
$237M
|
+$1.59M
|
+13,303
|
+0.6%
|
|
|
7
|
Avoro Capital Advisors
New York
|
$227M
|
+$20.9M
|
+175,000
|
+10%
|
|
|
8
|
Eventide Asset Management
Boston,
Massachusetts
|
$196M
|
–
|
–
|
–
|
|
|
9
|
Artisan Partners
Milwaukee,
Wisconsin
|
$183M
|
+$55.3M
|
+462,160
|
+41%
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$177M
|
+$4.79M
|
+40,000
|
+3%
|
|
|
11
|
Millennium Management
New York
|
$129M
|
-$31.3M
|
-261,355
|
-19%
|
|
|
12
|
Sofinnova Investments
Menlo Park,
California
|
$127M
|
+$12.1M
|
+101,286
|
+10%
|
|
|
13
|
|
$117M
|
+$111M
|
+924,169
|
+1,025%
|
|
|
14
|
Westfield Capital Management
Boston,
Massachusetts
|
$112M
|
+$34.1M
|
+285,207
|
+42%
|
|
|
15
|
Franklin Resources
San Mateo,
California
|
$101M
|
-$33.9K
|
-283
|
-0%
|
|
|
16
|
Marshall Wace North America
New York
|
$101M
|
-$34.4M
|
-287,831
|
-25%
|
|
|
17
|
Lakewood Capital Management
New York
|
$88.5M
|
-$28.7M
|
-240,000
|
-24%
|
|
|
18
|
Camber Capital Management
Boston,
Massachusetts
|
$74.8M
|
+$26.3M
|
+220,000
|
+51%
|
|
|
19
|
VHCP Management II
New York
|
$58.1M
|
–
|
–
|
–
|
|
|
20
|
AllianceBernstein
Nashville,
Tennessee
|
$58M
|
-$12.9M
|
-107,449
|
-18%
|
|
|
21
|
Great Point Partners
Greenwich,
Connecticut
|
$57.6M
|
+$10.2M
|
+85,000
|
+20%
|
|
|
22
|
Perceptive Advisors
New York
|
$54.5M
|
-$76.6M
|
-639,853
|
-57%
|
|
|
23
|
|
$52.3M
|
+$3.69M
|
+30,827
|
+7%
|
|
|
24
|
Cormorant Asset Management
Boston,
Massachusetts
|
$46.1M
|
-$23.9M
|
-200,000
|
-33%
|
|
|
25
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$44.3M
|
+$12.7M
|
+106,214
|
+38%
|
|
