|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$552M
|
+$42.9M
|
+489,461
|
+12%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$550M
|
+$48.9M
|
+558,110
|
+14%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$486M
|
-$9.47M
|
-108,094
|
-3%
|
|
|
4
|
|
$467M
|
-$10.2M
|
-116,700
|
-3%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$399M
|
+$48.4M
|
+552,918
|
+19%
|
|
|
6
|
Vivo Capital
Palo Alto,
California
|
$241M
|
-$10.5M
|
-120,000
|
-6%
|
|
|
7
|
Avoro Capital Advisors
New York
|
$211M
|
-$16.2M
|
-185,000
|
-9%
|
|
|
8
|
Eventide Asset Management
Boston,
Massachusetts
|
$200M
|
–
|
–
|
–
|
|
|
9
|
Farallon Capital Management
San Francisco,
California
|
$177M
|
+$61.6K
|
+703
|
+0%
|
|
|
10
|
Millennium Management
New York
|
$162M
|
+$105M
|
+1,194,634
|
+650%
|
|
|
11
|
Marshall Wace North America
New York
|
$137M
|
+$36.7M
|
+418,717
|
+56%
|
|
|
12
|
Artisan Partners
Milwaukee,
Wisconsin
|
$133M
|
+$66.9M
|
+764,160
|
+208%
|
|
|
13
|
Perceptive Advisors
New York
|
$131M
|
+$5.31M
|
+60,681
|
+6%
|
|
|
14
|
Lakewood Capital Management
New York
|
$119M
|
+$17.4M
|
+198,600
|
+25%
|
|
|
15
|
Sofinnova Investments
Menlo Park,
California
|
$118M
|
-$43.8M
|
-500,000
|
-33%
|
|
|
16
|
Franklin Resources
San Mateo,
California
|
$103M
|
+$22.6M
|
+257,589
|
+42%
|
|
|
17
|
Westfield Capital Management
Boston,
Massachusetts
|
$80.8M
|
+$12.9M
|
+147,425
|
+27%
|
|
|
18
|
AllianceBernstein
Nashville,
Tennessee
|
$71.9M
|
-$6.64M
|
-75,790
|
-11%
|
|
|
19
|
Cormorant Asset Management
Boston,
Massachusetts
|
$70.6M
|
+$22.9M
|
+261,544
|
+77%
|
|
|
20
|
VHCP Management II
New York
|
$59.3M
|
–
|
–
|
–
|
|
|
21
|
Camber Capital Management
Boston,
Massachusetts
|
$50.6M
|
+$37.7M
|
+430,000
|
New
|
|
|
22
|
OppenheimerFunds
New York
|
$50.2M
|
-$89.5K
|
-1,022
|
-0.2%
|
|
|
23
|
|
$49.8M
|
-$2.01M
|
-22,906
|
-5%
|
|
|
24
|
Great Point Partners
Greenwich,
Connecticut
|
$48.8M
|
+$36.3M
|
+415,000
|
New
|
|
|
25
|
Ghost Tree Capital
New York
|
$45.3M
|
+$22.8M
|
+260,000
|
+208%
|
|
