|
1
|
|
$294M
|
+$68.8M
|
+1,045,976
|
+31%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$282M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$222M
|
-$25.3M
|
-384,738
|
-10%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$206M
|
+$18.5M
|
+281,261
|
+10%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$189M
|
–
|
–
|
–
|
|
|
6
|
Sofinnova Investments
Menlo Park,
California
|
$165M
|
–
|
–
|
–
|
|
|
7
|
Vivo Capital
Palo Alto,
California
|
$144M
|
–
|
–
|
–
|
|
|
8
|
Avoro Capital Advisors
New York
|
$137M
|
–
|
–
|
–
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$97.4M
|
-$23.6M
|
-358,508
|
-20%
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$96.9M
|
+$11.2M
|
+170,497
|
+13%
|
|
|
11
|
Eventide Asset Management
Boston,
Massachusetts
|
$92.3M
|
+$3.58M
|
+54,460
|
+4%
|
|
|
12
|
Perceptive Advisors
New York
|
$71.4M
|
+$5.92M
|
+90,000
|
+9%
|
|
|
13
|
AllianceBernstein
Nashville,
Tennessee
|
$46.3M
|
-$2.5M
|
-38,056
|
-5%
|
|
|
14
|
Marshall Wace North America
New York
|
$42.5M
|
+$4.38M
|
+66,676
|
+12%
|
|
|
15
|
Millennium Management
New York
|
$37.7M
|
-$6.48M
|
-98,504
|
-15%
|
|
|
16
|
Franklin Resources
San Mateo,
California
|
$36.5M
|
+$3.15M
|
+47,931
|
+10%
|
|
|
17
|
VHCP Management II
New York
|
$33.5M
|
-$5.39M
|
-81,985
|
-14%
|
|
|
18
|
Deerfield Management
New York
|
$32.1M
|
–
|
–
|
–
|
|
|
19
|
Lakewood Capital Management
New York
|
$30M
|
+$29.6M
|
+450,526
|
New
|
|
|
20
|
|
$29.2M
|
+$2.17M
|
+32,980
|
+8%
|
|
|
21
|
OppenheimerFunds
New York
|
$28.5M
|
+$33.5K
|
+510
|
+0.1%
|
|
|
22
|
Westfield Capital Management
Boston,
Massachusetts
|
$28.2M
|
+$27.9M
|
+424,575
|
New
|
|
|
23
|
Cormorant Asset Management
Boston,
Massachusetts
|
$24.7M
|
–
|
–
|
–
|
|
|
24
|
|
$23.6M
|
–
|
–
|
–
|
|
|
25
|
Acuta Capital Partners
Redwood City,
California
|
$20.7M
|
-$15.3M
|
-232,889
|
-43%
|
|
