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Ascendis Pharma A/S

273 hedge funds and large institutions have $14.3B invested in Ascendis Pharma A/S in 2026 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 108 increasing their positions, 106 reducing their positions, and 58 closing their positions.

New
Increased
Maintained
Reduced
Closed

477% more call options, than puts

Call options by funds: $341M | Put options by funds: $59M

33% more funds holding in top 10

Funds holding in top 10: 1216 (+4)

4% more capital invested

Capital invested by funds: $13.8B → $14.3B (+$537M)

2% more repeat investments, than reductions

Existing positions increased: 108 | Existing positions reduced: 106

3.9% less ownership

Funds ownership: 104.44%100.54% (-3.9%)

10% less funds holding

Funds holding: 302273 (-29)

41% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 58

Holders
273
Holders Change
-29
Holders Change %
-9.6%
% of All Funds
3.36%
Holding in Top 10
16
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+33.33%
% of All Funds
0.2%
New
34
Increased
108
Reduced
106
Closed
58
Calls
$341M
Puts
$59M
Net Calls
+$282M
Net Calls Change
+$153M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$2.35B
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$1.41B +$1.01B +4,494,417 +270%
ACA
3
Avoro Capital Advisors
New York
$1.16B -$10.9M -48,611 -1%
Westfield Capital Management
4
Westfield Capital Management
Massachusetts
$1.1B -$83.4M -372,256 -7%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$887M -$62M -276,710 -7%
Artisan Partners
6
Artisan Partners
Wisconsin
$739M +$965K +4,303 +0.1%
Franklin Resources
7
Franklin Resources
California
$469M +$31.8M +141,869 +7%
Capital International Investors
8
Capital International Investors
California
$448M -$248M -1,105,100 -36%
Massachusetts Financial Services
9
Massachusetts Financial Services
Massachusetts
$426M -$5.77M -25,724 -1%
Wellington Management Group
10
Wellington Management Group
Massachusetts
$402M -$1.14M -5,088 -0.3%
PA
11
Perceptive Advisors
New York
$350M +$101M +450,000 +42%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$350M -$8.95M -39,915 -3%
American Century Companies
13
American Century Companies
Missouri
$320M -$10.3M -46,022 -3%
Capital World Investors
14
Capital World Investors
California
$206M +$202M +900,517 New
Principal Financial Group
15
Principal Financial Group
Iowa
$205M -$29.1M -130,010 -13%
BlackRock
16
BlackRock
New York
$151M +$7.36M +32,854 +5%
PCH
17
Polar Capital Holdings
United Kingdom
$149M +$63M +281,239 +76%
Morgan Stanley
18
Morgan Stanley
New York
$139M -$2.6M -11,620 -2%
Goldman Sachs
19
Goldman Sachs
New York
$130M -$6.84M -30,511 -5%
NAMI
20
Nomura Asset Management International
Pennsylvania
$127M +$13.4M +59,590 +12%
JP Morgan Chase
21
JP Morgan Chase
New York
$118M +$7.22M +32,194 +6%
Ameriprise
22
Ameriprise
Minnesota
$109M -$16.6M -74,011 -13%
Fidelity International
23
Fidelity International
Bermuda
$102M -$7M -31,220 -7%
VPC
24
Vestal Point Capital
New York
$85.8M +$44.8M +200,000 +114%
SCM
25
Spyglass Capital Management
California
$84.2M -$10.7M -47,577 -11%

ASND Hedge Fund Activity: Q1 2026 in Review

273 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q1 2026, worth a combined $14.3B — up 3.9% from $13.8B a quarter earlier.

Sellers outnumbered buyers: 58 funds closed out of ASND and 34 opened new positions — a net loss of 24 holders — while 106 trimmed existing stakes and 108 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $1.01B. The largest seller was Janus Henderson Group, exiting entirely with an estimated $866M sold.

  • 273 institutional investors held Ascendis Pharma A/S (ASND) as of Q1 2026, down from 302 in Q4 2025.
  • Funds reported $14.3B of Ascendis Pharma A/S stock for Q1 2026, up 3.9% quarter-over-quarter.
  • 34 funds opened new Ascendis Pharma A/S positions in Q1 2026 and 58 closed out, a net change of -24 holders.
  • The largest Ascendis Pharma A/S buyer in Q1 2026 was T. Rowe Price Investment Management, an estimated $1.01B added.
  • The largest Ascendis Pharma A/S seller in Q1 2026 was Janus Henderson Group, an estimated $866M sold.

Based on aggregated 13F filings for Q1 2026.