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Ascendis Pharma A/S

247 hedge funds and large institutions have $10.9B invested in Ascendis Pharma A/S in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 82 increasing their positions, 88 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

210% more call options, than puts

Call options by funds: $39.2M | Put options by funds: $12.6M

14% more funds holding in top 10

Funds holding in top 10: 1416 (+2)

10% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 40

7% more capital invested

Capital invested by funds: $10.1B → $10.9B (+$708M)

1% more funds holding

Funds holding: 244247 (+3)

7% less repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 88

4.51% less ownership

Funds ownership: 107.4%102.88% (-4.5%)

Holders
247
Holders Change
+3
Holders Change %
+1.23%
% of All Funds
3.25%
Holding in Top 10
16
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+14.29%
% of All Funds
0.21%
New
44
Increased
82
Reduced
88
Closed
40
Calls
$39.2M
Puts
$12.6M
Net Calls
+$26.6M
Net Calls Change
+$41.1M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$1.77B
Westfield Capital Management
2
Westfield Capital Management
Massachusetts
$941M -$4.54M -27,858 -0.5%
ACA
3
Avoro Capital Advisors
New York
$860M -$38.8M -238,000 -5%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$782M -$23M -141,219 -3%
Janus Henderson Group
5
Janus Henderson Group
United Kingdom
$764M -$9.64M -59,157 -1%
Artisan Partners
6
Artisan Partners
Wisconsin
$689M -$43.4M -266,203 -6%
T. Rowe Price Investment Management
7
T. Rowe Price Investment Management
Maryland
$619M +$86.3M +529,722 +17%
Capital International Investors
8
Capital International Investors
California
$526M +$28M +172,139 +6%
Massachusetts Financial Services
9
Massachusetts Financial Services
Massachusetts
$328M +$3.9M +23,926 +1%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$324M -$62M -380,611 -17%
Franklin Resources
11
Franklin Resources
California
$303M +$18.5M +113,347 +7%
PA
12
Perceptive Advisors
New York
$166M +$157M +963,886 New
Invesco
13
Invesco
Georgia
$163M -$40.9M -251,252 -21%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$158M +$53.8M +330,332 +56%
PCH
15
Polar Capital Holdings
United Kingdom
$145M +$50.9M +312,777 +60%
Ameriprise
16
Ameriprise
Minnesota
$102M -$15M -91,874 -14%
Citadel Advisors
17
Citadel Advisors
Florida
$101M -$87.6M -537,841 -48%
Goldman Sachs
18
Goldman Sachs
New York
$92.9M -$7.7M -47,294 -8%
American Century Companies
19
American Century Companies
Missouri
$91.6M +$11.2M +68,638 +15%
BlackRock
20
BlackRock
New York
$81.4M -$7.4M -45,428 -9%
Fidelity International
21
Fidelity International
Bermuda
$80.1M +$282K +1,730 +0.4%
Adage Capital Partners
22
Adage Capital Partners
Massachusetts
$79.3M +$21.5M +132,201 +40%
AllianceBernstein
23
AllianceBernstein
Tennessee
$65.2M -$8.86M -54,397 -13%
WP
24
Woodline Partners
California
$52.7M +$106K +648 +0.2%
TD Asset Management
25
TD Asset Management
Ontario, Canada
$50.4M -$8.36M -51,300 -15%

ASND Hedge Fund Activity: Q2 2025 in Review

247 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q2 2025, worth a combined $10.9B — up 7% from $10.1B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new ASND positions and 40 closed out — a net gain of 4 holders — while 82 added to existing stakes and 88 trimmed.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $157M. The largest seller was Morgan Stanley, cutting an estimated $269M.

  • 247 institutional investors held Ascendis Pharma A/S (ASND) as of Q2 2025, up from 244 in Q1 2025.
  • Funds reported $10.9B of Ascendis Pharma A/S stock for Q2 2025, up 7% quarter-over-quarter.
  • 44 funds opened new Ascendis Pharma A/S positions in Q2 2025 and 40 closed out, a net change of +4 holders.
  • The largest Ascendis Pharma A/S buyer in Q2 2025 was Perceptive Advisors, an estimated $157M added.
  • The largest Ascendis Pharma A/S seller in Q2 2025 was Morgan Stanley, an estimated $269M sold.

Based on aggregated 13F filings for Q2 2025.