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Ascendis Pharma A/S

302 hedge funds and large institutions have $13.8B invested in Ascendis Pharma A/S in 2025 Q4 according to their latest regulatory filings, with 62 funds opening new positions, 121 increasing their positions, 91 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

211% more call options, than puts

Call options by funds: $189M | Put options by funds: $60.8M

68% more first-time investments, than exits

New positions opened: 62 | Existing positions closed: 37

33% more repeat investments, than reductions

Existing positions increased: 121 | Existing positions reduced: 91

9% more capital invested

Capital invested by funds: $12.7B → $13.8B (+$1.09B)

8% more funds holding

Funds holding: 279302 (+23)

0.91% more ownership

Funds ownership: 103.53%104.44% (+0.91%)

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
302
Holders Change
+23
Holders Change %
+8.24%
% of All Funds
3.67%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.15%
New
62
Increased
121
Reduced
91
Closed
37
Calls
$189M
Puts
$60.8M
Net Calls
+$128M
Net Calls Change
+$43.4M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$2.19B
Westfield Capital Management
2
Westfield Capital Management
Massachusetts
$1.11B -$15.3M -74,213 -1%
ACA
3
Avoro Capital Advisors
New York
$1.09B +$229K +1,111 +0%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$886M -$65.8M -318,422 -7%
Janus Henderson Group
5
Janus Henderson Group
United Kingdom
$866M -$54M -261,418 -6%
Artisan Partners
6
Artisan Partners
Wisconsin
$688M -$102M -494,995 -13%
Capital International Investors
7
Capital International Investors
California
$653M +$687K +3,327 +0.1%
Franklin Resources
8
Franklin Resources
California
$407M +$66.1M +320,123 +20%
Massachusetts Financial Services
9
Massachusetts Financial Services
Massachusetts
$402M +$746K +3,612 +0.2%
Wellington Management Group
10
Wellington Management Group
Massachusetts
$376M -$7.48M -36,210 -2%
T. Rowe Price Investment Management
11
T. Rowe Price Investment Management
Maryland
$356M -$206M -998,993 -37%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$335M -$32.2M -155,968 -9%
American Century Companies
13
American Century Companies
Missouri
$308M +$186M +898,535 +165%
PA
14
Perceptive Advisors
New York
$231M -$1.46M -7,080 -0.7%
Principal Financial Group
15
Principal Financial Group
Iowa
$219M +$48.1M +232,730 +29%
BlackRock
16
BlackRock
New York
$134M +$36.5M +176,703 +39%
Morgan Stanley
17
Morgan Stanley
New York
$132M +$43.6M +211,207 +52%
Goldman Sachs
18
Goldman Sachs
New York
$127M -$11.6M -56,309 -9%
Invesco
19
Invesco
Georgia
$125M -$68.5M -331,809 -36%
Ameriprise
20
Ameriprise
Minnesota
$117M -$2.57M -12,459 -2%
Citadel Advisors
21
Citadel Advisors
Florida
$111M +$102M +491,876 +1,780%
JP Morgan Chase
22
JP Morgan Chase
New York
$108M +$44.4M +214,844 +73%
NAMI
23
Nomura Asset Management International
Pennsylvania
$106M +$103M +496,837 New
Fidelity International
24
Fidelity International
Bermuda
$102M +$3.99M +19,301 +4%
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$100M +$97.3M +470,951 New