|
1
|
RA Capital Management
Boston,
Massachusetts
|
$277M
|
-$75.3M
|
-1,340,154
|
-24%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$244M
|
+$5.3M
|
+94,308
|
+3%
|
|
|
3
|
|
$220M
|
–
|
–
|
–
|
|
|
4
|
Baker Bros. Advisors
New York
|
$186M
|
+$12.3M
|
+218,534
|
+8%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$184M
|
+$133M
|
+2,363,868
|
+521%
|
|
|
6
|
Sofinnova Investments
Menlo Park,
California
|
$162M
|
+$139M
|
+2,479,514
|
New
|
|
|
7
|
Vivo Capital
Palo Alto,
California
|
$142M
|
+$22.5M
|
+400,000
|
+23%
|
|
|
8
|
Avoro Capital Advisors
New York
|
$135M
|
+$21.5M
|
+382,312
|
+23%
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$119M
|
-$16M
|
-285,025
|
-14%
|
|
|
10
|
Eventide Asset Management
Boston,
Massachusetts
|
$87.1M
|
–
|
–
|
–
|
|
|
11
|
Farallon Capital Management
San Francisco,
California
|
$84.2M
|
+$72.3M
|
+1,286,800
|
New
|
|
|
12
|
Perceptive Advisors
New York
|
$64.3M
|
+$55.2M
|
+982,647
|
New
|
|
|
13
|
AllianceBernstein
Nashville,
Tennessee
|
$48M
|
+$38.1M
|
+677,843
|
+1,220%
|
|
|
14
|
Millennium Management
New York
|
$43.5M
|
+$7.58M
|
+134,936
|
+25%
|
|
|
15
|
VHCP Management II
New York
|
$38.3M
|
-$29.6M
|
-526,819
|
-47%
|
|
|
16
|
Adage Capital Partners
Boston,
Massachusetts
|
$37.6M
|
+$31.2M
|
+556,000
|
+2,926%
|
|
|
17
|
Marshall Wace North America
New York
|
$37.5M
|
+$11.6M
|
+206,627
|
+56%
|
|
|
18
|
Acuta Capital Partners
Redwood City,
California
|
$35.6M
|
+$731K
|
+13,000
|
+2%
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$32.8M
|
+$28.2M
|
+501,167
|
New
|
|
|
20
|
Deerfield Management
New York
|
$31.6M
|
-$17.2M
|
-306,533
|
-39%
|
|
|
21
|
Foresite Capital Management IV
Larkspur,
California
|
$31.1M
|
-$3.03M
|
-53,924
|
-10%
|
|
|
22
|
OppenheimerFunds
New York
|
$28M
|
+$7.34M
|
+130,540
|
+44%
|
|
|
23
|
|
$26.5M
|
-$1.44M
|
-25,533
|
-6%
|
|
|
24
|
Cormorant Asset Management
Boston,
Massachusetts
|
$24.3M
|
+$4.03M
|
+71,739
|
+24%
|
|
|
25
|
|
$23.2M
|
–
|
–
|
–
|
|
