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Arrowhead Research

265 hedge funds and large institutions have $1.34B invested in Arrowhead Research in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 89 increasing their positions, 82 reducing their positions, and 46 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 82

7% less first-time investments, than exits

New positions opened: 43 | Existing positions closed: 46

1% less funds holding

Funds holding: 269265 (-4)

3.44% less ownership

Funds ownership: 80.16%76.72% (-3.4%)

25% less call options, than puts

Call options by funds: $4.66M | Put options by funds: $6.24M

28% less capital invested

Capital invested by funds: $1.88B → $1.34B (-$532M)

Holders
265
Holders Change
-4
Holders Change %
-1.49%
% of All Funds
3.55%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
43
Increased
89
Reduced
82
Closed
46
Calls
$4.66M
Puts
$6.24M
Net Calls
-$1.58M
Net Calls Change
-$3.28M
Name Holding Trade Value Shares
Change
Change in
Stake
Thrivent Financial for Lutherans
76
Thrivent Financial for Lutherans
Minnesota
$1.18M +$1.15M +63,370 +217%
JF
77
Jump Financial
Illinois
$1.12M -$959K -52,755 -37%
Luther King Capital Management (LKCM)
78
Luther King Capital Management (LKCM)
Texas
$1.06M +$120K +6,625 +9%
BNP Paribas Financial Markets
79
BNP Paribas Financial Markets
France
$1.06M -$94.7K -5,206 -6%
IIM
80
INTECH Investment Management
Florida
$1.05M -$118K -6,508 -7%
HF
81
HRT Financial
New York
$937K -$83K -4,565 -6%
MIM
82
MetLife Investment Management
New Jersey
$917K -$1.26M -69,048 -49%
GCP
83
GSA Capital Partners
United Kingdom
$913K +$1.09M +60,018 +514%
MF
84
Magnetar Financial
Illinois
$897K +$1.02M +56,008 +390%
SOADOR
85
State of Alaska Department of Revenue
Alaska
$890K +$1.01M +55,708 +393%
SG Americas Securities
86
SG Americas Securities
New York
$871K +$1.24M +68,346 New
MCM
87
M28 Capital Management
Connecticut
$859K
Wells Fargo
88
Wells Fargo
California
$858K +$81K +4,454 +7%
CP
89
CenterBook Partners
Connecticut
$852K -$5.16M -283,560 -81%
State of Wisconsin Investment Board
90
State of Wisconsin Investment Board
Wisconsin
$845K +$5.09K +280 +0.4%
Tudor Investment Corp
91
Tudor Investment Corp
Connecticut
$837K -$15.7K -865 -1%
Manulife (Manufacturers Life Insurance)
92
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$837K -$1.32M -72,609 -53%
CF
93
Corebridge Financial
Texas
$797K -$2.48M -136,598 -69%
Marshall Wace
94
Marshall Wace
United Kingdom
$761K -$489K -26,873 -31%
LSERS
95
Louisiana State Employees Retirement System
Louisiana
$757K +$453K +24,900 +72%
Simplex Trading
96
Simplex Trading
Illinois
$727K +$742K +40,785 +250%
TD Asset Management
97
TD Asset Management
Ontario, Canada
$721K -$131K -7,178 -11%
ACM
98
ADAR1 Capital Management
Texas
$717K +$789K +43,400 +336%
FRM
99
Fox Run Management
Connecticut
$706K +$55.7K +3,062 +6%
State of Tennessee, Department of Treasury
100
State of Tennessee, Department of Treasury
Tennessee
$704K +$445K +24,488 +80%

ARWR Hedge Fund Activity: Q1 2025 in Review

265 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Arrowhead Research (ARWR) for Q1 2025, worth a combined $1.34B — down 28% from $1.88B a quarter earlier.

Sellers outnumbered buyers: 46 funds closed out of ARWR and 43 opened new positions — a net loss of 3 holders — while 82 trimmed existing stakes and 89 added.

The largest buyer was BlackRock, adding an estimated $68.2M. The largest seller was Fidelity Investments, cutting an estimated $32.5M.

  • 265 institutional investors held Arrowhead Research (ARWR) as of Q1 2025, down from 269 in Q4 2024.
  • Funds reported $1.34B of Arrowhead Research stock for Q1 2025, down 28% quarter-over-quarter.
  • 43 funds opened new Arrowhead Research positions in Q1 2025 and 46 closed out, a net change of -3 holders.
  • The largest Arrowhead Research buyer in Q1 2025 was BlackRock, an estimated $68.2M added.
  • The largest Arrowhead Research seller in Q1 2025 was Fidelity Investments, an estimated $32.5M sold.

Based on aggregated 13F filings for Q1 2025.