|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$412M
|
+$41.5M
|
+2,711,240
|
+11%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$337M
|
-$13.5M
|
-882,864
|
-4%
|
|
|
3
|
|
$260M
|
+$3.09M
|
+201,556
|
+1%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$242M
|
-$1.1M
|
-71,900
|
-0.4%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$136M
|
+$19.2M
|
+1,253,175
|
+16%
|
|
|
6
|
Franklin Resources
San Mateo,
California
|
$120M
|
-$6.22M
|
-406,186
|
-5%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$95.6M
|
+$24.8M
|
+1,618,391
|
+35%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$93.5M
|
-$7.2M
|
-470,067
|
-7%
|
|
|
9
|
Baker Bros. Advisors
New York
|
$86M
|
–
|
–
|
–
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$77.9M
|
+$7.28M
|
+475,000
|
+10%
|
|
|
11
|
|
$73.1M
|
-$1.44M
|
-94,000
|
-2%
|
|
|
12
|
|
$53.8M
|
-$3.69M
|
-240,718
|
-6%
|
|
|
13
|
Millennium Management
New York
|
$49.3M
|
+$32.4M
|
+2,115,447
|
+188%
|
|
|
14
|
American Century Companies
Kansas City,
Missouri
|
$47.4M
|
+$7.76M
|
+506,146
|
+19%
|
|
|
15
|
|
$44.3M
|
-$10.1M
|
-661,116
|
-18%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$39.3M
|
+$951K
|
+62,053
|
+2%
|
|
|
17
|
Wells Fargo
San Francisco,
California
|
$37.8M
|
+$4.49M
|
+292,749
|
+13%
|
|
|
18
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$37.6M
|
+$10.4M
|
+677,180
|
+38%
|
|
|
19
|
Driehaus Capital Management
Chicago,
Illinois
|
$36.4M
|
-$3.4M
|
-221,921
|
-8%
|
|
|
20
|
First Light Asset Management
Edina,
Minnesota
|
$36.2M
|
-$160K
|
-10,429
|
-0.4%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$35.3M
|
+$2.14M
|
+139,860
|
+6%
|
|
|
22
|
VOYA Investment Management
Atlanta,
Georgia
|
$35M
|
+$4.63M
|
+301,965
|
+15%
|
|
|
23
|
Alkeon Capital Management
New York
|
$34.4M
|
+$4.83M
|
+315,262
|
+16%
|
|
|
24
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$31.8M
|
+$8.09M
|
+527,690
|
+34%
|
|
|
25
|
|
$29.5M
|
+$2.82M
|
+184,084
|
+10%
|
|
