|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$385M
|
+$22.8M
|
+1,421,000
|
+6%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$358M
|
+$3.21M
|
+200,347
|
+0.9%
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$281M
|
-$30.3M
|
-1,889,436
|
-10%
|
|
|
4
|
|
$260M
|
+$11.2M
|
+696,635
|
+5%
|
|
|
5
|
Franklin Resources
San Mateo,
California
|
$134M
|
-$15.2M
|
-946,069
|
-10%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$130M
|
-$21.3M
|
-1,330,140
|
-14%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$98.7M
|
+$39.5M
|
+2,465,357
|
+69%
|
|
|
8
|
Baker Bros. Advisors
New York
|
$92.3M
|
–
|
–
|
–
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$82.6M
|
-$58M
|
-3,623,730
|
-42%
|
|
|
10
|
|
$80M
|
-$43.6M
|
-2,720,500
|
-36%
|
|
|
11
|
Farallon Capital Management
San Francisco,
California
|
$50.5M
|
+$49.6M
|
+3,095,000
|
New
|
|
|
12
|
|
$50.5M
|
-$9.11M
|
-568,466
|
-16%
|
|
|
13
|
EcoR1 Capital
San Francisco,
California
|
$49.8M
|
+$2.67M
|
+166,600
|
+6%
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$44M
|
+$2.94M
|
+183,264
|
+7%
|
|
|
15
|
Pinnacle Associates
New York
|
$42.4M
|
-$1.89M
|
-118,155
|
-4%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$39.5M
|
+$555K
|
+34,658
|
+1%
|
|
|
17
|
Wells Fargo
San Francisco,
California
|
$39.2M
|
-$632K
|
-39,440
|
-2%
|
|
|
18
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$33.9M
|
+$11.1M
|
+694,571
|
+50%
|
|
|
19
|
|
$32.6M
|
+$8.01M
|
+500,000
|
+33%
|
|
|
20
|
|
$32.5M
|
-$1.98M
|
-123,321
|
-6%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$32.3M
|
+$1.82M
|
+113,861
|
+6%
|
|
|
22
|
Avoro Capital Advisors
New York
|
$31.4M
|
-$56.8M
|
-3,545,374
|
-65%
|
|
|
23
|
|
$31M
|
+$15.6M
|
+976,565
|
+106%
|
|
|
24
|
|
$28.7M
|
–
|
–
|
–
|
|
|
25
|
First Light Asset Management
Edina,
Minnesota
|
$27.3M
|
+$1.74M
|
+108,344
|
+7%
|
|
