|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$137M
|
+$52.1M
|
+7,315,521
|
+65%
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$96.7M
|
+$9.02M
|
+1,267,300
|
+11%
|
|
|
3
|
Deerfield Management
New York
|
$87.2M
|
–
|
–
|
–
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$69.3M
|
-$16.8M
|
-2,366,518
|
-20%
|
|
|
5
|
|
$68M
|
+$14.1M
|
+1,984,610
|
+27%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$56.1M
|
-$7.72M
|
-1,085,000
|
-12%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$41.7M
|
+$30.1M
|
+4,224,958
|
+295%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$41.5M
|
+$3.96M
|
+555,868
|
+11%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$35.9M
|
+$214K
|
+30,107
|
+0.6%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$35.6M
|
+$3.17M
|
+444,821
|
+10%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$29.9M
|
+$565K
|
+79,429
|
+2%
|
|
|
12
|
Pinnacle Associates
New York
|
$29.1M
|
+$139K
|
+19,515
|
+0.5%
|
|
|
13
|
TimesSquare Capital Management
New York
|
$28.1M
|
-$2.03M
|
-285,700
|
-7%
|
|
|
14
|
|
$27.3M
|
+$5.05M
|
+710,000
|
+24%
|
|
|
15
|
Millennium Management
New York
|
$19M
|
+$11.9M
|
+1,672,260
|
+185%
|
|
|
16
|
|
$13.4M
|
+$12.9M
|
+1,813,209
|
New
|
|
|
17
|
|
$11.9M
|
+$2.28M
|
+320,000
|
+25%
|
|
|
18
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$11.9M
|
+$1.83M
|
+256,822
|
+19%
|
|
|
19
|
Apex Capital
Orinda,
California
|
$11.4M
|
-$3.22M
|
-452,700
|
-23%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$10.8M
|
+$577K
|
+81,029
|
+6%
|
|
|
21
|
Bogle Investment Management
Newton Lower Falls,
Massachusetts
|
$10.7M
|
+$10.3M
|
+1,450,173
|
New
|
|
|
22
|
RA Capital Management
Boston,
Massachusetts
|
$10M
|
+$9.66M
|
+1,357,584
|
New
|
|
|
23
|
Renaissance Technologies
New York
|
$7.77M
|
+$7.51M
|
+1,054,652
|
New
|
|
|
24
|
|
$7.46M
|
+$5.65M
|
+793,130
|
+362%
|
|
|
25
|
City National Bank
Beverly Hills,
Delaware
|
$7.27M
|
+$1.73M
|
+243,485
|
+33%
|
|
