|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$133M
|
-$333K
|
-45,100
|
-0.2%
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$98.2M
|
+$3.68M
|
+498,026
|
+4%
|
|
|
3
|
|
$72.5M
|
+$6.11M
|
+828,190
|
+9%
|
|
|
4
|
Deerfield Management
New York
|
$68.7M
|
-$17M
|
-2,305,234
|
-19%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$66.1M
|
-$1.75M
|
-236,541
|
-3%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$52.5M
|
-$2.46M
|
-332,900
|
-4%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$45.5M
|
+$10.9M
|
+1,482,167
|
+31%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$40.8M
|
+$5.77M
|
+781,466
|
+16%
|
|
|
9
|
Baker Bros. Advisors
New York
|
$39.5M
|
-$1.3M
|
-176,250
|
-3%
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
$37.3M
|
-$3.44M
|
-465,816
|
-8%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$27.8M
|
-$1.42M
|
-192,958
|
-5%
|
|
|
12
|
Pinnacle Associates
New York
|
$27.5M
|
-$933K
|
-126,430
|
-3%
|
|
|
13
|
TimesSquare Capital Management
New York
|
$27.3M
|
-$160K
|
-21,655
|
-0.6%
|
|
|
14
|
|
$26.7M
|
–
|
–
|
–
|
|
|
15
|
|
$13.9M
|
+$866K
|
+117,330
|
+6%
|
|
|
16
|
Millennium Management
New York
|
$11.8M
|
-$6.97M
|
-944,983
|
-37%
|
|
|
17
|
|
$11.4M
|
-$284K
|
-38,500
|
-2%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$11.4M
|
+$858K
|
+116,333
|
+8%
|
|
|
19
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$11.2M
|
-$466K
|
-63,164
|
-4%
|
|
|
20
|
|
$8.48M
|
+$1.21M
|
+164,314
|
+16%
|
|
|
21
|
Two Sigma Investments
New York
|
$7.28M
|
+$1.44M
|
+195,412
|
+24%
|
|
|
22
|
Columbus Circle Investors
|
$6.71M
|
-$142K
|
-19,256
|
-2%
|
|
|
23
|
|
$6.63M
|
–
|
–
|
–
|
|
|
24
|
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
$6.43M
|
-$529K
|
-71,700
|
-7%
|
|
|
25
|
Cormorant Asset Management
Boston,
Massachusetts
|
$6.13M
|
–
|
–
|
–
|
|
