|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$284M
|
-$632K
|
-55,600
|
-0.3%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$278M
|
+$22M
|
+1,936,270
|
+10%
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$245M
|
+$17.7M
|
+1,557,278
|
+9%
|
|
|
4
|
|
$195M
|
+$19.4M
|
+1,707,369
|
+13%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$119M
|
+$21.1M
|
+1,852,419
|
+25%
|
|
|
6
|
Franklin Resources
San Mateo,
California
|
$117M
|
+$11.1M
|
+979,072
|
+12%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$111M
|
+$26M
|
+2,283,973
|
+36%
|
|
|
8
|
|
$97.6M
|
-$74.6M
|
-6,561,500
|
-46%
|
|
|
9
|
Point72 Asset Management
Stamford,
Connecticut
|
$73.1M
|
-$37.5M
|
-3,296,373
|
-37%
|
|
|
10
|
Baker Bros. Advisors
New York
|
$72.4M
|
+$5.04M
|
+442,668
|
+8%
|
|
|
11
|
Avoro Capital Advisors
New York
|
$70M
|
+$1.31M
|
+115,000
|
+2%
|
|
|
12
|
|
$47.1M
|
+$12.6M
|
+1,104,917
|
+43%
|
|
|
13
|
|
$46.9M
|
+$16.3M
|
+1,436,294
|
+65%
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$45.9M
|
-$935K
|
-82,243
|
-2%
|
|
|
15
|
EcoR1 Capital
San Francisco,
California
|
$36.9M
|
+$18.6M
|
+1,632,712
|
+131%
|
|
|
16
|
Millennium Management
New York
|
$36M
|
-$1.81M
|
-159,477
|
-5%
|
|
|
17
|
Pinnacle Associates
New York
|
$34.8M
|
-$2.86M
|
-251,125
|
-8%
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
$32.2M
|
+$4.73M
|
+416,277
|
+20%
|
|
|
19
|
Wells Fargo
San Francisco,
California
|
$31.3M
|
-$1.62M
|
-142,839
|
-6%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$30.5M
|
+$3.01M
|
+264,241
|
+12%
|
|
|
21
|
|
$27M
|
+$15.2M
|
+1,338,377
|
+173%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$23.9M
|
+$952K
|
+83,705
|
+5%
|
|
|
23
|
Balyasny Asset Management
Chicago,
Illinois
|
$23.3M
|
+$16.8M
|
+1,479,245
|
+431%
|
|
|
24
|
|
$22.5M
|
–
|
–
|
–
|
|
|
25
|
First Light Asset Management
Edina,
Minnesota
|
$20.1M
|
+$1.11M
|
+97,343
|
+7%
|
|
