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Amylyx Pharmaceuticals
AMLX

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$200M +$69.8M +5,139,212 +45%
BlackRock
2
BlackRock
New York
$109M +$26M +1,913,739 +27%
PA
3
Perceptive Advisors
New York
$100M -$9.07M -667,483 -7%
TCM
4
TCG Crossover Management
California
$75.4M – – –
Vanguard Group
5
Vanguard Group
Pennsylvania
$70.1M +$7.21M +531,162 +10%
CC
6
Commodore Capital
New York
$68.3M +$21.4M +1,574,522 +39%
SVCM
7
Saturn V Capital Management
Texas
$54.3M -$1.47M -108,391 -2%
Janus Henderson Group
8
Janus Henderson Group
$54M +$26.2M +1,929,639 +76%
FLAM
9
First Light Asset Management
Minnesota
$40.5M -$4.66K -343 -0%
DCM
10
Driehaus Capital Management
Illinois
$37.6M +$9.35M +688,736 +28%
Adage Capital Partners
11
Adage Capital Partners
Massachusetts
$33.5M -$54.9M -4,039,773 -59%
Goldman Sachs
12
Goldman Sachs
New York
$31.6M +$8.18M +602,588 +30%
Morgan Stanley
13
Morgan Stanley
New York
$28.5M +$5.56M +409,523 +21%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$26.2M +$4.8M +353,495 +20%
AC
15
Almitas Capital
California
$25.6M – – –
State Street
16
State Street
Massachusetts
$25M +$6.09M +448,624 +28%
GPP
17
Great Point Partners
Connecticut
$21.1M +$679K +50,000 +3%
6CM
18
683 Capital Management
New York
$19.9M -$1.49M -110,000 -6%
EAM
19
Eventide Asset Management
Massachusetts
$18.3M +$8.8K +648 +0%
Bank of America
20
Bank of America
North Carolina
$16.1M +$12.3M +906,494 +211%
Deutsche Bank
21
Deutsche Bank
Germany
$16.1M -$439K -32,285 -2%
Franklin Resources
22
Franklin Resources
California
$14.5M +$16.3M +1,200,096 New
Connor, Clark & Lunn Investment Management (CC&L)
23
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$12.1M -$1.4M -102,987 -9%
LGM
24
Logos Global Management
California
$11.5M -$6.79M -500,000 -34%
Northern Trust
25
Northern Trust
Illinois
$11.3M +$1.57M +115,527 +14%
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