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Amylyx Pharmaceuticals
AMLX

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$155M +$78.4M +8,331,188 +273%
PA
2
Perceptive Advisors
New York
$122M +$9.88M +1,050,000 +13%
BlackRock
3
BlackRock
New York
$97M +$15.3M +1,630,503 +30%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$92.6M -$18.7M -1,983,172 -23%
TCM
5
TCG Crossover Management
California
$84.9M +$2.82M +300,000 +5%
Vanguard Group
6
Vanguard Group
Pennsylvania
$71.7M +$7.3M +775,722 +17%
SVCM
7
Saturn V Capital Management
Texas
$62.6M +$12.7M +1,344,308 +41%
CC
8
Commodore Capital
New York
$55.4M +$38.4M +4,075,478 New
FLAM
9
First Light Asset Management
Minnesota
$45.6M +$31.6M +3,355,882 New
Point72 Asset Management
10
Point72 Asset Management
Connecticut
$37.9M -$16.4M -1,746,200 -38%
Janus Henderson Group
11
Janus Henderson Group
$34.5M +$23.9M +2,536,233 New
DCM
12
Driehaus Capital Management
Illinois
$32.9M +$10.9M +1,155,770 +91%
AC
13
Almitas Capital
California
$28.8M – – –
Goldman Sachs
14
Goldman Sachs
New York
$27.3M +$6.71M +712,651 +55%
Morgan Stanley
15
Morgan Stanley
New York
$26.5M +$13.8M +1,463,408 +301%
PBA
16
Paradigm Biocapital Advisors
New York
$25.8M +$17.9M +1,900,000 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$24.6M +$1.13M +119,626 +7%
6CM
18
683 Capital Management
New York
$23.9M -$3.76M -400,000 -19%
GPP
19
Great Point Partners
Connecticut
$23.1M -$2.82M -300,000 -15%
State Street
20
State Street
Massachusetts
$22M +$5.76M +612,351 +61%
EAM
21
Eventide Asset Management
Massachusetts
$20.6M +$14.2M +1,512,500 New
Balyasny Asset Management
22
Balyasny Asset Management
Illinois
$20.1M +$13.9M +1,476,302 New
LGM
23
Logos Global Management
California
$19.7M +$13.6M +1,450,000 New
UBS Group
24
UBS Group
Switzerland
$19.1M +$1.42M +151,127 +12%
Deutsche Bank
25
Deutsche Bank
Germany
$18.6M +$7.05M +748,602 +121%
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