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Amylyx Pharmaceuticals

122 hedge funds and large institutions have $188M invested in Amylyx Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 35 increasing their positions, 40 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

65% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 20

34% more capital invested

Capital invested by funds: $141M → $188M (+$47.6M)

11% more funds holding

Funds holding: 110122 (+12)

8.85% more ownership

Funds ownership: 63.82%72.67% (+8.8%)

13% less repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 40

30% less call options, than puts

Call options by funds: $1.36M | Put options by funds: $1.94M

Holders
122
Holders Change
+12
Holders Change %
+10.91%
% of All Funds
1.61%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
33
Increased
35
Reduced
40
Closed
20
Calls
$1.36M
Puts
$1.94M
Net Calls
-$579K
Net Calls Change
+$1.67M
Name Holding Trade Value Shares
Change
Change in
Stake
AGM
76
Alpine Global Management
New York
$90.8K +$113K +24,034 New
PCM
77
Parsons Capital Management
Rhode Island
$81.8K -$1.41K -300 -1%
MG
78
Marex Group
$75.6K -$94.1K -20,000 -50%
Brown Advisory
79
Brown Advisory
Maryland
$75.3K -$94 -20 -0.1%
WS
80
Wedbush Securities
California
$75K +$93.7K +19,914 New
Prudential Financial
81
Prudential Financial
New Jersey
$73.3K
Simplex Trading
82
Simplex Trading
Illinois
$67K -$442K -93,909 -84%
VPIM
83
Vanguard Personalized Indexing Management
California
$67K +$5.33K +1,132 +7%
EGM
84
Engineers Gate Manager
New York
$66.7K +$83K +17,637 New
SOW
85
State of Wyoming
Wyoming
$60.8K -$45.6K -9,700 -38%
SG Americas Securities
86
SG Americas Securities
New York
$60K -$195K -41,428 -72%
YIH
87
Y-Intercept (HK)
Hong Kong
$56K +$69.7K +14,809 New
CUAMC
88
China Universal Asset Management Company
China
$54.9K +$6.78K +1,441 +11%
EC
89
EntryPoint Capital
New York
$52.6K +$65.5K +13,909 New
RL
90
RPO LLC
Connecticut
$45.9K +$57.1K +12,136 New
Royal Bank of Canada
91
Royal Bank of Canada
Ontario, Canada
$45K +$113 +24 +0.2%
Bank of Nova Scotia
92
Bank of Nova Scotia
Ontario, Canada
$44.9K +$5.59K +1,188 +11%
FRM
93
Fox Run Management
Connecticut
$44.6K +$55.5K +11,788 New
HSBC Holdings
94
HSBC Holdings
United Kingdom
$43.3K -$236K -50,121 -81%
VA
95
Vident Advisory
Georgia
$41.1K -$22.2K -4,710 -30%
GCP
96
GSA Capital Partners
United Kingdom
$40K +$50.1K +10,639 New
RS
97
R Squared
Hong Kong
$24.1K +$30K +6,370 New
Russell Investments Group
98
Russell Investments Group
United Kingdom
$19.2K -$9.04K -1,920 -27%
PD
99
Point72 (DIFC)
United Arab Emirates
$18.1K +$22.6K +4,796 New
US Bancorp
100
US Bancorp
Minnesota
$15.1K +$18.8K +4,000 New

AMLX Hedge Fund Activity: Q4 2024 in Review

122 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Amylyx Pharmaceuticals (AMLX) for Q4 2024, worth a combined $188M — up 34% from $141M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new AMLX positions and 20 closed out — a net gain of 13 holders — while 35 added to existing stakes and 40 trimmed.

The largest buyer was Perceptive Advisors, adding an estimated $21.9M. The largest seller was Alyeska Investment Group, cutting an estimated $5.65M.

  • 122 institutional investors held Amylyx Pharmaceuticals (AMLX) as of Q4 2024, up from 110 in Q3 2024.
  • Funds reported $188M of Amylyx Pharmaceuticals stock for Q4 2024, up 34% quarter-over-quarter.
  • 33 funds opened new Amylyx Pharmaceuticals positions in Q4 2024 and 20 closed out, a net change of +13 holders.
  • The largest Amylyx Pharmaceuticals buyer in Q4 2024 was Perceptive Advisors, an estimated $21.9M added.
  • The largest Amylyx Pharmaceuticals seller in Q4 2024 was Alyeska Investment Group, an estimated $5.65M sold.

Based on aggregated 13F filings for Q4 2024.