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Amylyx Pharmaceuticals

171 hedge funds and large institutions have $1.59B invested in Amylyx Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 53 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

4% less funds holding

Funds holding: 179171 (-8)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

19% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 36

Holders
171
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$9.02M
Puts
$1.5M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
ACM
26
ADAR1 Capital Management
Texas
$13.9M
Barclays
27
Barclays
United Kingdom
$13.5M
VPM
28
Vanguard Portfolio Management
Pennsylvania
$13.1M
Dimensional Fund Advisors
29
Dimensional Fund Advisors
Texas
$12.5M
Connor, Clark & Lunn Investment Management (CC&L)
30
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$12.1M
WP
31
Woodline Partners
California
$11.8M
BCM
32
Boxer Capital Management
California
$11.1M
Northern Trust
33
Northern Trust
Illinois
$10.8M
Charles Schwab
34
Charles Schwab
California
$9.96M
Qube Research & Technologies (QRT)
35
Qube Research & Technologies (QRT)
United Kingdom
$9.76M
LGM
36
Logos Global Management
California
$9.73M
SC
37
Stempoint Capital
New York
$9.31M
PHP
38
Parkman Healthcare Partners
Connecticut
$8.64M
JAM
39
Jupiter Asset Management
United Kingdom
$8.24M
VFT
40
Vanguard Fiduciary Trust
Pennsylvania
$8.15M
NCM
41
Nantahala Capital Management
Connecticut
$7.45M
RSCM
42
Rock Springs Capital Management
Maryland
$6.95M
Citadel Advisors
43
Citadel Advisors
Florida
$5.72M
Federated Hermes
44
Federated Hermes
Pennsylvania
$5.05M
HS
45
HighVista Strategies
Massachusetts
$4.89M
CAM
46
Cormorant Asset Management
Massachusetts
$4.87M
UBS Group
47
UBS Group
Switzerland
$4.51M
TAM
48
TFG Asset Management
Cayman Islands
$4.42M
IGAM
49
iA Global Asset Management
Quebec, Canada
$4.24M
N
50
Nuveen
North Carolina
$3.68M