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Alnylam Pharmaceuticals

784 hedge funds and large institutions have $40.1B invested in Alnylam Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 87 funds opening new positions, 319 increasing their positions, 280 reducing their positions, and 80 closing their positions.

New
Increased
Maintained
Reduced
Closed

113% more call options, than puts

Call options by funds: $453M | Put options by funds: $213M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

14% more repeat investments, than reductions

Existing positions increased: 319 | Existing positions reduced: 280

9% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 80

0.64% more ownership

Funds ownership: 99.08%99.72% (+0.64%)

1% less funds holding

Funds holding: 791784 (-7)

8% less capital invested

Capital invested by funds: $43.4B → $40.1B (-$3.32B)

Holders
784
Holders Change
-7
Holders Change %
-0.88%
% of All Funds
9.47%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
87
Increased
319
Reduced
280
Closed
80
Calls
$453M
Puts
$213M
Net Calls
+$240M
Net Calls Change
-$5M
Name Holding Trade Value Shares
Change
Change in
Stake
CIBC Asset Management
201
CIBC Asset Management
Ontario, Canada
$8.83M -$39.2K -130 -0.4%
SLAM
202
Swiss Life Asset Management
$8.83M +$1.69M +5,593 +24%
CI
203
Capital International
California
$8.78M +$26.5K +88 +0.3%
FCM
204
Frontier Capital Management
Massachusetts
$8.75M -$467K -1,548 -5%
Mariner
205
Mariner
Kansas
$8.43M -$581K -1,927 -6%
EI
206
EFG International
$8.16M +$464K +1,539 +6%
LIP
207
Liontrust Investment Partners
United Kingdom
$8.06M +$2.58M +8,541 +47%
Nordea Investment Management
208
Nordea Investment Management
Sweden
$8.03M +$4.09M +13,567 +102%
Daiwa Securities Group
209
Daiwa Securities Group
Japan
$7.8M +$163K +540 +2%
CII
210
Capital International Inc
California
$7.73M +$36.5K +121 +0.5%
CUAMC
211
China Universal Asset Management Company
China
$7.61M -$602K -1,997 -7%
PSC
212
Portman Square Capital
United Kingdom
$7.53M +$2.44M +8,092 +48%
SG Americas Securities
213
SG Americas Securities
New York
$7.5M -$9.09M -30,149 -55%
O
214
Ossiam
France
$7.47M +$192K +638 +3%
IMRF
215
Illinois Municipal Retirement Fund
Illinois
$7.31M -$6.03K -20 -0.1%
Corient Private Wealth
216
Corient Private Wealth
Florida
$7.16M -$579K -1,921 -7%
Cetera Investment Advisers
217
Cetera Investment Advisers
Illinois
$6.98M +$6.94K +23 +0.1%
ECSS
218
Eurizon Capital SGR SpA
$6.83M -$448K -1,486 -6%
QC
219
Quadrature Capital
United Kingdom
$6.82M -$18.9M -62,588 -73%
P
220
PensionDanmark
Denmark
$6.76M -$3.66M -12,119 -35%
Toronto Dominion Bank
221
Toronto Dominion Bank
Ontario, Canada
$6.69M +$1.09M +3,613 +19%
Creative Planning
222
Creative Planning
Kansas
$6.67M -$589K -1,954 -8%
JFG
223
Jefferies Financial Group
New York
$6.65M -$1.04M -3,458 -14%
Macquarie Group
224
Macquarie Group
Australia
$6.3M +$1.48M +4,896 +31%
CFM
225
Catalyst Funds Management
Australia
$6.26M +$6.27M +20,803 New

ALNY Hedge Fund Activity: Q2 2026 in Review

784 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Alnylam Pharmaceuticals (ALNY) for Q2 2026, worth a combined $40.1B — down 7.7% from $43.4B a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new ALNY positions and 80 closed out — a net gain of 7 holders — while 319 added to existing stakes and 280 trimmed.

The largest buyer was Deep Track Capital, opening a new position worth an estimated $249M. The largest seller was JP Morgan Chase, cutting an estimated $1.1B.

  • 784 institutional investors held Alnylam Pharmaceuticals (ALNY) as of Q2 2026, down from 791 in Q1 2026.
  • Funds reported $40.1B of Alnylam Pharmaceuticals stock for Q2 2026, down 7.7% quarter-over-quarter.
  • 87 funds opened new Alnylam Pharmaceuticals positions in Q2 2026 and 80 closed out, a net change of +7 holders.
  • The largest Alnylam Pharmaceuticals buyer in Q2 2026 was Deep Track Capital, an estimated $249M added.
  • The largest Alnylam Pharmaceuticals seller in Q2 2026 was JP Morgan Chase, an estimated $1.1B sold.

Based on aggregated 13F filings for Q2 2026.