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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
$196M
2
Holocene Advisors
Holocene Advisors
New York
$195M
3
ClearBridge Investments
ClearBridge Investments
New York
$182M
4
Macquarie Group
Macquarie Group
Australia
$196M
5
Fidelity Investments
Fidelity Investments
Massachusetts
$5.15B

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
$61.3M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$989M
3
Wellington Management Group
Wellington Management Group
Massachusetts
$677M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$1.03B
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
GAM
201
Gotham Asset Management
New York
$5.8M +$1.07M +3,270 +23%
CGIM
202
Capital Group Investment Management
Singapore
$5.78M +$127K +388 +2%
Assenagon Asset Management
203
Assenagon Asset Management
Luxembourg
$5.77M +$3.68M +11,281 +176%
Jacobs Levy Equity Management
204
Jacobs Levy Equity Management
New Jersey
$5.76M -$44.1M -135,296 -88%
JF
205
Jump Financial
Illinois
$5.6M +$476K +1,460 +9%
JG
206
Jain Global
New York
$5.46M +$3.43M +10,509 +169%
NAM
207
Nissay Asset Management
Japan
$5.31M +$24.1K +74 +0.5%
MOACM
208
Mutual of America Capital Management
New York
$5.2M +$751K +2,302 +17%
Creative Planning
209
Creative Planning
Kansas
$5.08M -$169K -519 -3%
Hudson Bay Capital Management
210
Hudson Bay Capital Management
Connecticut
$5M +$5M +15,348 New
Mariner
211
Mariner
Kansas
$4.91M +$61.9K +190 +1%
JSSH
212
J. Safra Sarasin Holding
$4.89M -$469K -1,439 -9%
SMDAM
213
Sumitomo Mitsui DS Asset Management
Japan
$4.83M +$604K +1,851 +14%
EMPI
214
Elo Mutual Pension Insurance
Finland
$4.61M +$1.05M +3,222 +30%
Stifel Financial
215
Stifel Financial
Missouri
$4.47M +$2.16M +6,627 +94%
AS
216
Aware Super
Australia
$4.46M – – –
HCS
217
Himension Capital (Singapore)
Singapore
$4.4M -$592K -1,816 -12%
QCM
218
Quantinno Capital Management
New York
$4.39M +$2.29M +7,032 +109%
VPIM
219
Vanguard Personalized Indexing Management
California
$4.37M +$1.4M +4,302 +47%
PNC Financial Services Group
220
PNC Financial Services Group
Pennsylvania
$4.29M +$14.7K +45 +0.3%
Bank of Montreal
221
Bank of Montreal
Ontario, Canada
$4.28M +$791K +2,427 +23%
MASUI
222
MIRAE ASSET SECURITIES (USA) INC.
New York
$4.25M +$4.25M +13,034 New
Daiwa Securities Group
223
Daiwa Securities Group
Japan
$4.22M +$11.4K +35 +0.3%
Public Employees Retirement Association of Colorado
224
Public Employees Retirement Association of Colorado
Colorado
$4.19M -$75.6K -232 -2%
LIP
225
Liontrust Investment Partners
United Kingdom
$4.16M -$1.99M -6,111 -32%
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