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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
$196M
2
Holocene Advisors
Holocene Advisors
New York
$195M
3
ClearBridge Investments
ClearBridge Investments
New York
$182M
4
Macquarie Group
Macquarie Group
Australia
$196M
5
Fidelity Investments
Fidelity Investments
Massachusetts
$5.15B

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
$61.3M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$989M
3
Wellington Management Group
Wellington Management Group
Massachusetts
$677M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$1.03B
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
FRAF
176
Första AP-fonden
Sweden
$8.61M +$196K +600 +2%
UIM
177
USS Investment Management
United Kingdom
$8.59M – – –
IMRF
178
Illinois Municipal Retirement Fund
Illinois
$8.49M -$11.9M -36,619 -58%
II
179
IFM Investors
Australia
$8.27M +$492K +1,508 +6%
X
180
Xponance
Pennsylvania
$8.16M +$607K +1,860 +8%
Toronto Dominion Bank
181
Toronto Dominion Bank
Ontario, Canada
$7.71M +$1.38M +4,246 +22%
KCM
182
Kornitzer Capital Management
Kansas
$7.55M +$6.9M +21,164 +1,058%
CCM
183
Cinctive Capital Management
New York
$7.46M -$650K -1,994 -8%
Jane Street
184
Jane Street
New York
$7.45M -$24.7M -75,695 -77%
BBVA
185
Banco Bilbao Vizcaya Argentaria
Spain
$7.26M -$167K -512 -2%
EAM
186
EFG Asset Management
Oregon
$6.89M -$1.15M -3,529 -14%
IMPI
187
Ilmarinen Mutual Pension Insurance
Finland
$6.85M +$6.85M +21,000 New
AGP
188
Artia Global Partners
Florida
$6.84M -$2.49M -7,630 -27%
URS
189
Utah Retirement Systems
Utah
$6.84M -$116K -355 -2%
TI
190
Trexquant Investment
Connecticut
$6.7M +$6.7M +20,543 New
BCIM
191
British Columbia Investment Management
British Columbia, Canada
$6.68M -$1.37M -4,195 -17%
Caisse de Depot et Placement du Quebec (CDPQ)
192
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$6.54M -$1.21M -3,719 -16%
PE
193
Point72 Europe
United Kingdom
$6.5M +$1.3M +3,976 +25%
SCM
194
Silvant Capital Management
Georgia
$6.31M +$1.03M +3,152 +19%
BFM
195
Boothbay Fund Management
New York
$6.27M +$2.97M +9,123 +90%
PFSRSONJ
196
Police & Firemen's Retirement System of New Jersey
New Jersey
$6.18M +$69.1K +212 +1%
Comerica Bank
197
Comerica Bank
Texas
$6.07M +$445K +1,364 +8%
HF
198
HRT Financial
New York
$5.83M -$12.2M -37,286 -68%
FTM
199
First Turn Management
California
$5.83M +$5.83M +17,879 New
MML Investors Services
200
MML Investors Services
Massachusetts
$5.82M +$1.6M +4,911 +38%
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