Two Sigma Investments
VRTX icon

Two Sigma Investments’s Vertex Pharmaceuticals VRTX Stock Holding History

Two Sigma Investments’s Portfolio VRTX Stock Details VRTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2017
Q2 		– Sell
-7,900
Closed -$864K – 3310
2017
Q1 		$864K Buy
+7,900
New +$696K ﹤0.01% 2009
2016
Q3 		– Sell
-7,700
Closed -$662K – 3408
2016
Q2 		$662K Buy
+7,700
New +$665K ﹤0.01% 2051

Other funds holding VRTX

Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Capital Research Global Investors
Capital Research Global Investors Los Angeles, California $645B AUM 30.41% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Capital International Investors
Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return

Two Sigma Investments's VRTX Position: Q1 2026 in Review

Two Sigma Investments increased its Vertex Pharmaceuticals (VRTX) stake by 9,001% in Q1 2026, buying an estimated $174M and bringing the position to 378,146 shares worth $169M. The position accounts for 0.14% of the portfolio, ranked #168.

Two Sigma Investments first reported a position in VRTX in Q2 2015 and has held it in 34 quarters since. The position peaked at $174M in Q3 2021. 1,687 funds tracked by Wall St. Rank hold VRTX as of Q1 2026.

  • Two Sigma Investments held 378,146 shares of Vertex Pharmaceuticals worth $169M as of Q1 2026.
  • Two Sigma Investments bought 373,991 Vertex Pharmaceuticals shares in Q1 2026, an estimated $174M.
  • Vertex Pharmaceuticals made up 0.14% of Two Sigma Investments's portfolio in Q1 2026, its #168 holding.
  • Two Sigma Investments first reported a position in Vertex Pharmaceuticals in Q2 2015 and has held it in 34 quarters since.
  • Two Sigma Investments's Vertex Pharmaceuticals position peaked at $174M in Q3 2021.
  • 1,687 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.