Two Sigma Investments’s Guardant Health GH Stock Holding History

Two Sigma Investments’s Portfolio GH Stock Details GH Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-2,000	Closed	-$204K	–	4714
2025 Q4	$204K	Buy	+2,000	New	+$179K	﹤0.01%	3756
2022 Q1	–	Sell	-8,000	Closed	-$800K	–	3293
2021 Q4	$800K	Buy	8,000 +5,800	+264%	+$600K	﹤0.01%	2767
2021 Q3	$275K	Sell	2,200 -1,700	-44%	-$202K	﹤0.01%	3737
2021 Q2	$484K	Buy	+3,900	New	+$525K	﹤0.01%	3133
2020 Q2	–	Sell	-22,200	Closed	-$1.54M	–	3155
2020 Q1	$1.54M	Buy	22,200 +17,900	+416%	+$1.37M	0.01%	1117
2019 Q4	$336K	Sell	4,300 -3,900	-48%	-$281K	﹤0.01%	3100
2019 Q3	$523K	Buy	8,200 +5,800	+242%	+$511K	﹤0.01%	2522
2019 Q2	$207K	Buy	+2,400	New	+$183K	﹤0.01%	3069

Other funds holding GH

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return

Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Baillie Gifford & Co Edinburgh, United Kingdom $97.9B AUM 20.73% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return

Two Sigma Investments's GH Position: Q1 2026 in Review

Two Sigma Investments increased its Guardant Health (GH) stake by 95% in Q1 2026, buying an estimated $207M and bringing the position to 4,229,531 shares worth $391M. The position accounts for 0.32% of the portfolio, ranked #56.

Two Sigma Investments first reported a position in GH in Q3 2019 and has held it in 21 quarters since. 481 funds tracked by Wall St. Rank hold GH as of Q1 2026.

Two Sigma Investments held 4,229,531 shares of Guardant Health worth $391M as of Q1 2026.
Two Sigma Investments bought 2,057,628 Guardant Health shares in Q1 2026, an estimated $207M.
Guardant Health made up 0.32% of Two Sigma Investments's portfolio in Q1 2026, its #56 holding.
Two Sigma Investments first reported a position in Guardant Health in Q3 2019 and has held it in 21 quarters since.
481 funds tracked by Wall St. Rank held Guardant Health as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.