Two Sigma Advisers’s Fulcrum Therapeutics FULC Stock Holding History

Two Sigma Advisers’s Portfolio FULC Stock Details FULC Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-30,500	Closed	-$345K	–	828
2025 Q4	$345K	Sell	30,500 -1,000	-3%	-$10.2K	﹤0.01%	1935
2025 Q3	$290K	Sell	31,500 -50,600	-62%	-$366K	﹤0.01%	2003
2025 Q2	$565K	Sell	82,100 -195,700	-70%	-$1.05M	﹤0.01%	1696
2025 Q1	$800K	Sell	277,800 -65,800	-19%	-$242K	﹤0.01%	1571
2024 Q4	$1.61M	Sell	343,600 -38,600	-10%	-$142K	﹤0.01%	1221
2024 Q3	$1.36M	Sell	382,200 -181,300	-32%	-$1.35M	﹤0.01%	1268
2024 Q2	$3.49M	Buy	563,500 +143,300	+34%	+$1.09M	0.01%	921
2024 Q1	$3.97M	Sell	420,200 -76,000	-15%	-$678K	0.01%	871
2023 Q4	$3.35M	Sell	496,200 -25,800	-5%	-$114K	0.01%	1011
2023 Q3	$2.32M	Sell	522,000 -73,300	-12%	-$320K	0.01%	1116
2023 Q2	$1.96M	Buy	595,300 +332,700	+127%	+$978K	0.01%	1209
2023 Q1	$748K	Buy	262,600 +198,600	+310%	+$1.78M	﹤0.01%	1771
2022 Q4	$466K	Buy	64,000 +13,700	+27%	+$89.3K	﹤0.01%	1906
2022 Q3	$407K	Sell	50,300 -61,000	-55%	-$437K	﹤0.01%	1933
2022 Q2	$545K	Buy	111,300 +25,800	+30%	+$252K	﹤0.01%	1875
2022 Q1	$2.02M	Sell	85,500 -293,600	-77%	-$4.16M	0.01%	1247
2021 Q4	$6.71M	Buy	379,100 +236,900	+167%	+$4.69M	0.02%	645
2021 Q3	$4.01M	Buy	+142,200	New	+$2.69M	0.01%	897

Other funds holding FULC

SCM

Suvretta Capital Management New York $5.47B AUM 131.34% 1-Year Est. Return

RCM

RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return

Braidwell Stamford, Connecticut $2.7B AUM 88.53% 1-Year Est. Return

NCM

Nantahala Capital Management New Canaan, Connecticut $3.01B AUM 119.46% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return

FTM

First Turn Management Del Mar, California $935M AUM 298.58% 1-Year Est. Return

Aberdeen Group Edinburgh, United Kingdom $71.2B AUM 41.74% 1-Year Est. Return

Two Sigma Advisers's FULC Position: Q1 2026 in Review

Two Sigma Advisers sold out of Fulcrum Therapeutics (FULC) in Q1 2026, closing a stake of 30,500 shares — an estimated $345K sold.

Two Sigma Advisers first reported a position in FULC in Q3 2021 and held it in 18 quarters. The position peaked at $6.71M in Q4 2021. 169 funds tracked by Wall St. Rank hold FULC as of Q1 2026.

Two Sigma Advisers reported no remaining Fulcrum Therapeutics position as of Q1 2026 after selling out during the quarter.
Two Sigma Advisers sold 30,500 Fulcrum Therapeutics shares in Q1 2026, an estimated $345K.
Two Sigma Advisers first reported a position in Fulcrum Therapeutics in Q3 2021 and held it in 18 quarters.
Two Sigma Advisers's Fulcrum Therapeutics position peaked at $6.71M in Q4 2021.
169 funds tracked by Wall St. Rank held Fulcrum Therapeutics as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.