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Siren LLC’s ProQR Therapeutics PRQR Stock Holding History

Siren LLC’s Portfolio PRQR Stock Details PRQR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-1,552,183
Closed -$3.31M – 126
2025
Q3 		$3.31M Hold
1,552,183
– – 0.13% 77
2025
Q2 		$3.17M Hold
1,552,183
– – 0.16% 77
2025
Q1 		$2.06M Sell
1,552,183
-22,817
-1% -$48.6K 0.12% 86
2024
Q4 		$4.17M Buy
+1,575,000
New +$5M 0.18% 70

Other funds holding PRQR

Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
PFM
Privium Fund Management Amsterdam, Netherlands $480M AUM 77.45% 1-Year Est. Return
Aberdeen Group
Aberdeen Group Edinburgh, United Kingdom $61.9B AUM 29.81% 1-Year Est. Return
AAA
Affinity Asset Advisors New York $1.94B AUM 374.45% 1-Year Est. Return
SCM
Sio Capital Management New York $697M AUM 79.73% 1-Year Est. Return
DCM
DAFNA Capital Management Los Angeles, California $440M AUM 109.12% 1-Year Est. Return
KCM
Kynam Capital Management Princeton, New Jersey $1.62B AUM 138.67% 1-Year Est. Return
IC
Ikarian Capital Dallas, Texas $1.23B AUM 600.17% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
PIM
Platinum Investment Management Sydney Australia 2000, Australia $397M AUM 63.96% 1-Year Est. Return

Siren LLC's PRQR Position: Q4 2025 in Review

Siren LLC sold out of ProQR Therapeutics (PRQR) in Q4 2025, closing a stake of 1,552,183 shares — an estimated $3.31M sold.

Siren LLC first reported a position in PRQR in Q4 2024 and held it in 4 quarters. The position peaked at $4.17M in Q4 2024. 65 funds tracked by Wall St. Rank hold PRQR as of Q4 2025.

  • Siren LLC reported no remaining ProQR Therapeutics position as of Q4 2025 after selling out during the quarter.
  • Siren LLC sold 1,552,183 ProQR Therapeutics shares in Q4 2025, an estimated $3.31M.
  • Siren LLC first reported a position in ProQR Therapeutics in Q4 2024 and held it in 4 quarters.
  • Siren LLC's ProQR Therapeutics position peaked at $4.17M in Q4 2024.
  • 65 funds tracked by Wall St. Rank held ProQR Therapeutics as of Q4 2025.

Based on Siren LLC's 13F filing for Q4 2025, filed 13 Feb 2026.