Simplex Trading
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Simplex Trading’s Madrigal Pharmaceuticals MDGL Stock Holding History

Simplex Trading’s Portfolio MDGL Stock Details MDGL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.2M Buy
+4,200
New +$2.01M ﹤0.01% 1749
2025
Q4 		– Sell
-13,800
Closed -$6.33M – 9436
2025
Q3 		$6.33M Buy
13,800
+8,600
+165% +$3.21M ﹤0.01% 1268
2025
Q2 		$1.57M Sell
5,200
-3,800
-42% -$1.13M ﹤0.01% 2326
2025
Q1 		$2.98M Buy
9,000
+1,300
+17% +$427K ﹤0.01% 1667
2024
Q4 		$2.38M Sell
7,700
-400
-5% -$113K ﹤0.01% 2038
2024
Q3 		$1.72M Sell
8,100
-3,200
-28% -$819K ﹤0.01% 2410
2024
Q2 		$3.17M Sell
11,300
-11,300
-50% -$2.69M ﹤0.01% 1787
2024
Q1 		$6.04M Buy
22,600
+14,200
+169% +$3.35M ﹤0.01% 1462
2023
Q4 		$1.94M Sell
8,400
-6,800
-45% -$1.19M ﹤0.01% 2376
2023
Q3 		$2.22M Sell
15,200
-10,700
-41% -$2.01M ﹤0.01% 1985
2023
Q2 		$5.98M Buy
25,900
+5,500
+27% +$1.49M ﹤0.01% 1198
2023
Q1 		$4.94M Sell
20,400
-22,500
-52% -$6.13M ﹤0.01% 1315
2022
Q4 		$12.5M Buy
42,900
+36,600
+581% +$3.58M 0.01% 757
2022
Q3 		$409K Buy
6,300
+2,400
+62% +$167K ﹤0.01% 3699
2022
Q2 		$279K Sell
3,900
-3,500
-47% -$257K ﹤0.01% 4186
2022
Q1 		$726K Buy
7,400
+4,700
+174% +$396K ﹤0.01% 3343
2021
Q4 		$228K Buy
2,700
+2,500
+1,250% +$205K ﹤0.01% 4996
2021
Q3 		$19K Hold
200
– – ﹤0.01% 8481
2021
Q2 		$19K Buy
200
+198
+9,900% +$23.4K ﹤0.01% 8630
2021
Q1 		$23K Hold
2
– – ﹤0.01% 7345
2020
Q4 		$22K Sell
2
-156
-99% -$19.1K ﹤0.01% 6914
2020
Q3 		$1.88M Sell
158
-70
-31% -$7.6K ﹤0.01% 1598
2020
Q2 		$2.58M Sell
228
-46
-17% -$4.52K ﹤0.01% 1311
2020
Q1 		$1.83M Buy
274
+89
+48% +$7.42K ﹤0.01% 1349
2019
Q4 		$1.69M Buy
185
+98
+113% +$9.5K ﹤0.01% 1629
2019
Q3 		$750K Buy
87
+19
+28% +$1.78K ﹤0.01% 2232
2019
Q2 		$712K Sell
68
-122
-64% -$13.1K ﹤0.01% 2240
2019
Q1 		$2.38M Buy
190
+130
+217% +$16.2K 0.01% 1218
2018
Q4 		$676K Buy
60
+27
+82% +$4.18K ﹤0.01% 1954
2018
Q3 		$706K Buy
+33
New +$8.28K ﹤0.01% 2256
2016
Q1 		– Hold
0
– -$8K – 5958
2015
Q4 		– Hold
0
– – – 3508
2015
Q3 		– Hold
0
– – – 3739
2015
Q2 		– Hold
0
– – – 3525
2015
Q1 		– Hold
0
– – – 3362
2014
Q4 		– Hold
0
– – – 2659

Other funds holding MDGL

BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PC
Paulson & Co New York $3.11B AUM 94.93% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Simplex Trading's MDGL Position: Q4 2024 in Review

Simplex Trading sold out of Madrigal Pharmaceuticals (MDGL) in Q4 2024, closing a stake of 1,179 shares — an estimated $332K sold.

Simplex Trading first reported a position in MDGL in Q4 2014 and held it in 28 quarters. The position peaked at $5.23M in Q2 2023. 283 funds tracked by Wall St. Rank hold MDGL as of Q4 2024.

  • Simplex Trading reported no remaining Madrigal Pharmaceuticals position as of Q4 2024 after selling out during the quarter.
  • Simplex Trading sold 1,179 Madrigal Pharmaceuticals shares in Q4 2024, an estimated $332K.
  • Simplex Trading first reported a position in Madrigal Pharmaceuticals in Q4 2014 and held it in 28 quarters.
  • Simplex Trading's Madrigal Pharmaceuticals position peaked at $5.23M in Q2 2023.
  • 283 funds tracked by Wall St. Rank held Madrigal Pharmaceuticals as of Q4 2024.

Based on Simplex Trading's 13F filing for Q4 2024, filed 11 Feb 2025.