Royal Bank of Canada’s Ionis Pharmaceuticals IONS Stock Holding History

Royal Bank of Canada’s Portfolio IONS Stock Details IONS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-47,700	Closed	-$3.77M	–	7394
2025 Q4	$3.77M	Sell	47,700 -90,700	-66%	-$6.83M	﹤0.01%	2649
2025 Q3	$9.05M	Buy	138,400 +13,400	+11%	+$654K	﹤0.01%	2225
2025 Q2	$4.94M	Hold	125,000	–	–	﹤0.01%	2578
2025 Q1	$3.77M	Hold	125,000	–	–	﹤0.01%	2483
2024 Q4	$4.37M	Buy	+125,000	New	+$4.67M	﹤0.01%	2428
2024 Q2	–	Sell	-75,000	Closed	-$3.25M	–	7285
2024 Q1	$3.25M	Buy	+75,000	New	+$3.57M	﹤0.01%	2536
2019 Q1	–	Sell	-25,000	Closed	-$1.35M	–	6940
2018 Q4	$1.35M	Buy	+25,000	New	+$1.28M	﹤0.01%	2931
2018 Q2	–	Sell	-72,000	Closed	-$3.17M	–	6637
2018 Q1	$3.17M	Buy	+72,000	New	+$3.66M	﹤0.01%	2334
2017 Q3	–	Sell	-40,700	Closed	-$2.07M	–	6823
2017 Q2	$2.07M	Buy	+40,700	New	+$1.9M	﹤0.01%	2558
2017 Q1	–	Sell	-10,000	Closed	-$478K	–	6708
2016 Q4	$478K	Hold	10,000	–	–	﹤0.01%	3788
2016 Q3	$366K	Hold	10,000	–	–	﹤0.01%	3973
2016 Q2	$233K	Hold	10,000	–	–	﹤0.01%	4302
2016 Q1	$405K	Sell	10,000 -18,600	-65%	-$755K	﹤0.01%	3826
2015 Q4	$1.77M	Buy	28,600 +18,600	+186%	+$1M	﹤0.01%	2646
2015 Q3	$404K	Sell	10,000 -90,000	-90%	-$4.66M	﹤0.01%	3722
2015 Q2	$5.75M	Buy	+100,000	New	+$6.36M	﹤0.01%	1522
2014 Q2	–	Sell	-100,000	Closed	-$4.32M	–	6033
2014 Q1	$4.32M	Buy	+100,000	New	+$4.85M	﹤0.01%	1675

Other funds holding IONS

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return

Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Royal Bank of Canada's IONS Position: Q1 2026 in Review

Royal Bank of Canada increased its Ionis Pharmaceuticals (IONS) stake by 240% in Q1 2026, buying an estimated $212M and bringing the position to 3,801,815 shares worth $285M. The position accounts for 0.05% of the portfolio, ranked #328.

Royal Bank of Canada first reported a position in IONS in Q2 2013 and has held it in 52 quarters since. 494 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

Royal Bank of Canada held 3,801,815 shares of Ionis Pharmaceuticals worth $285M as of Q1 2026.
Royal Bank of Canada bought 2,683,018 Ionis Pharmaceuticals shares in Q1 2026, an estimated $212M.
Ionis Pharmaceuticals made up 0.05% of Royal Bank of Canada's portfolio in Q1 2026, its #328 holding.
Royal Bank of Canada first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 52 quarters since.
494 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on Royal Bank of Canada's 13F filing for Q1 2026, filed 15 May 2026.