Renaissance Technologies
SPRB

Renaissance Technologies’s Spruce Biosciences SPRB Stock Holding History

Renaissance Technologies’s Portfolio SPRB Stock Details SPRB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$254K Buy
+4,700
New +$263K ﹤0.01% 2826
2025
Q2 		– Sell
-5,105
Closed -$111K – 3993
2025
Q1 		$111K Sell
5,105
-307
-6% -$8.55K ﹤0.01% 3180
2024
Q4 		$170K Sell
5,412
-2,717
-33% -$99.6K ﹤0.01% 3205
2024
Q3 		$290K Buy
8,129
+3,248
+67% +$119K ﹤0.01% 2994
2024
Q2 		$190K Buy
4,881
+1,268
+35% +$68K ﹤0.01% 3056
2024
Q1 		$213K Buy
3,613
+1,145
+46% +$291K ﹤0.01% 3209
2023
Q4 		$542K Sell
2,468
-302
-11% -$34.9K ﹤0.01% 2739
2023
Q3 		$470K Sell
2,770
-418
-13% -$70.4K ﹤0.01% 2727
2023
Q2 		$514K Buy
3,188
+1,053
+49% +$176K ﹤0.01% 2857
2023
Q1 		$354K Buy
2,135
+289
+16% +$53.7K ﹤0.01% 3050
2022
Q4 		$152K Sell
1,846
-62
-3% -$5.19K ﹤0.01% 3506
2022
Q3 		$196K Sell
1,908
-111
-5% -$15.5K ﹤0.01% 3393
2022
Q2 		$263K Buy
2,019
+530
+36% +$67.9K ﹤0.01% 3526
2022
Q1 		$225K Buy
1,489
+958
+180% +$178K ﹤0.01% 3601
2021
Q4 		$178K Buy
531
+78
+17% +$23.2K ﹤0.01% 3555
2021
Q3 		$204K Buy
+453
New +$284K ﹤0.01% 3199

Other funds holding SPRB

ACM
AIGH Capital Management Baltimore, Maryland $1.59B AUM 855.46% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
IC
Ikarian Capital Dallas, Texas $928M AUM 596.14% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $2.19B AUM 374.99% 1-Year Est. Return
CCC
Cable Car Capital San Francisco, California $4.66B AUM 77.16% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
SC
Stempoint Capital New York $581M AUM 373.68% 1-Year Est. Return

Renaissance Technologies's SPRB Position: Q2 2026 in Review

Renaissance Technologies opened a new position in Spruce Biosciences (SPRB) in Q2 2026: 4,700 shares worth $254K. The stake represents ﹤0.01% of the portfolio and ranks #2826 among its holdings. This is a return to the name: Renaissance Technologies previously reported a position in SPRB as recently as Q1 2025.

Renaissance Technologies first reported a position in SPRB in Q3 2021 and has held it in 16 quarters since. The position peaked at $542K in Q4 2023. 57 funds tracked by Wall St. Rank hold SPRB as of Q2 2026.

  • Renaissance Technologies held 4,700 shares of Spruce Biosciences worth $254K as of Q2 2026.
  • Spruce Biosciences was a new Renaissance Technologies position in Q2 2026.
  • Spruce Biosciences made up ﹤0.01% of Renaissance Technologies's portfolio in Q2 2026, its #2826 holding.
  • Renaissance Technologies first reported a position in Spruce Biosciences in Q3 2021 and has held it in 16 quarters since.
  • Renaissance Technologies's Spruce Biosciences position peaked at $542K in Q4 2023.
  • 57 funds tracked by Wall St. Rank held Spruce Biosciences as of Q2 2026.

Based on Renaissance Technologies's 13F filing for Q2 2026, filed 13 Aug 2026.