Renaissance Technologies
SPRB icon

Renaissance Technologies’s Spruce Biosciences SPRB Stock Holding History

Renaissance Technologies’s Portfolio SPRB Stock Details SPRB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q3 		– Sell
-4,700
Closed -$254K – 3678
2026
Q2 		$254K Buy
+4,700
New +$263K ﹤0.01% 2826
2025
Q2 		– Sell
-5,105
Closed -$111K – 3993
2025
Q1 		$111K Sell
5,105
-307
-6% -$8.56K ﹤0.01% 3180
2024
Q4 		$170K Sell
5,412
-2,717
-33% -$100K ﹤0.01% 3205
2024
Q3 		$290K Buy
8,129
+3,248
+67% +$119K ﹤0.01% 2994
2024
Q2 		$190K Buy
4,881
+1,268
+35% +$68K ﹤0.01% 3056
2024
Q1 		$213K Buy
3,613
+1,145
+46% +$291K ﹤0.01% 3209
2023
Q4 		$542K Sell
2,468
-302
-11% -$34.9K ﹤0.01% 2739
2023
Q3 		$470K Sell
2,770
-418
-13% -$70.4K ﹤0.01% 2727
2023
Q2 		$514K Buy
3,188
+1,053
+49% +$176K ﹤0.01% 2857
2023
Q1 		$354K Buy
2,135
+289
+16% +$53.7K ﹤0.01% 3050
2022
Q4 		$152K Sell
1,846
-62
-3% -$5.19K ﹤0.01% 3506
2022
Q3 		$196K Sell
1,908
-111
-5% -$15.5K ﹤0.01% 3393
2022
Q2 		$263K Buy
2,019
+530
+36% +$67.9K ﹤0.01% 3526
2022
Q1 		$225K Buy
1,489
+958
+180% +$178K ﹤0.01% 3601
2021
Q4 		$178K Buy
531
+78
+17% +$23.2K ﹤0.01% 3555
2021
Q3 		$204K Buy
+453
New +$284K ﹤0.01% 3199

Other funds holding SPRB

ACM
AIGH Capital Management Baltimore, Maryland $992M AUM 516.32% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.76T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.92T AUM 36.1% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.44T AUM 36.12% 1-Year Est. Return
Carlyle Group
Carlyle Group Washington, District of Columbia $8.36B AUM 14.46% 1-Year Est. Return
Quinn Opportunity Partners
Quinn Opportunity Partners Charlottesville, Virginia $1.85B AUM 1.27% 1-Year Est. Return
DMKJ
David M. Knott Jr $183M AUM 73.23% 1-Year Est. Return
Vanguard Fiduciary Trust
Vanguard Fiduciary Trust Malvern, Pennsylvania $463B AUM
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.21T AUM
Persistent Asset Partners
Persistent Asset Partners Hong Kong $362M AUM 191.92% 1-Year Est. Return

Renaissance Technologies's SPRB Position: Q3 2026 in Review

Renaissance Technologies sold out of Spruce Biosciences (SPRB) in Q3 2026, closing a stake of 4,700 shares — an estimated $254K sold.

Renaissance Technologies first reported a position in SPRB in Q3 2021 and held it in 16 quarters. The position peaked at $542K in Q4 2023. 40 funds tracked by Wall St. Rank hold SPRB as of Q3 2026.

  • Renaissance Technologies reported no remaining Spruce Biosciences position as of Q3 2026 after selling out during the quarter.
  • Renaissance Technologies sold 4,700 Spruce Biosciences shares in Q3 2026, an estimated $254K.
  • Renaissance Technologies first reported a position in Spruce Biosciences in Q3 2021 and held it in 16 quarters.
  • Renaissance Technologies's Spruce Biosciences position peaked at $542K in Q4 2023.
  • 40 funds tracked by Wall St. Rank held Spruce Biosciences as of Q3 2026.

Based on Renaissance Technologies's 13F filing for Q3 2026, filed 12 Nov 2026.