Parnassus Investments
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Parnassus Investments’s Vertex Pharmaceuticals VRTX Stock Holding History

Parnassus Investments’s Portfolio VRTX Stock Details VRTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-1,648,433
Closed -$646M – 149
2025
Q3 		$646M Sell
1,648,433
-63,007
-4% -$26.3M 1.49% 27
2025
Q2 		$762M Sell
1,711,440
-61,278
-3% -$28.2M 1.76% 19
2025
Q1 		$859M Sell
1,772,718
-43,232
-2% -$20.1M 2.07% 16
2024
Q4 		$731M Buy
+1,815,950
New +$842M 1.62% 22
2024
Q1 		– Sell
-738
Closed -$300K – 142
2023
Q4 		$300K Buy
738
+74
+11% +$27.3K ﹤0.01% 130
2023
Q3 		$231K Buy
664
+50
+8% +$17.5K ﹤0.01% 136
2023
Q2 		$216K Sell
614
-152
-20% -$51.2K ﹤0.01% 133
2023
Q1 		$241K Sell
766
-239,515
-100% -$71.8M ﹤0.01% 133
2022
Q4 		$69.4M Sell
240,281
-21,686
-8% -$6.61M 0.17% 91
2022
Q3 		$75.8M Hold
261,967
– – 0.2% 85
2022
Q2 		$73.8M Sell
261,967
-309,518
-54% -$82.8M 0.18% 95
2022
Q1 		$149M Sell
571,485
-47,953
-8% -$11.4M 0.3% 75
2021
Q4 		$136M Hold
619,438
– – 0.26% 79
2021
Q3 		$112M Hold
619,438
– – 0.24% 85
2021
Q2 		$125M Buy
+619,438
New +$130M 0.27% 81

Other funds holding VRTX

Capital World Investors
Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Capital Research Global Investors
Capital Research Global Investors Los Angeles, California $717B AUM 35.42% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.26T AUM 61.52% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
Capital International Investors
Capital International Investors Los Angeles, California $484B AUM 34.9% 1-Year Est. Return
AllianceBernstein
AllianceBernstein Nashville, Tennessee $302B AUM 26.44% 1-Year Est. Return

Parnassus Investments's VRTX Position: Q4 2025 in Review

Parnassus Investments sold out of Vertex Pharmaceuticals (VRTX) in Q4 2025, closing a stake of 1,648,433 shares — an estimated $646M sold.

Parnassus Investments first reported a position in VRTX in Q2 2021 and held it in 15 quarters. The position peaked at $859M in Q1 2025. 1,670 funds tracked by Wall St. Rank hold VRTX as of Q4 2025.

  • Parnassus Investments reported no remaining Vertex Pharmaceuticals position as of Q4 2025 after selling out during the quarter.
  • Parnassus Investments sold 1,648,433 Vertex Pharmaceuticals shares in Q4 2025, an estimated $646M.
  • Parnassus Investments first reported a position in Vertex Pharmaceuticals in Q2 2021 and held it in 15 quarters.
  • Parnassus Investments's Vertex Pharmaceuticals position peaked at $859M in Q1 2025.
  • 1,670 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q4 2025.

Based on Parnassus Investments's 13F filing for Q4 2025, filed 12 Feb 2026.