Vanguard Group’s Vertex Pharmaceuticals VRTX Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q4
$10.9B Sell
24,105,823
-111,042
-0.5% -$47.9M 0.16% 103
2025
Q3
$9.48B Buy
24,216,865
+243,088
+1% +$102M 0.14% 118
2025
Q2
$10.7B Buy
23,973,777
+482,616
+2% +$222M 0.17% 98
2025
Q1
$11.4B Buy
23,491,161
+232,873
+1% +$109M 0.21% 84
2024
Q4
$9.37B Buy
23,258,288
+98,654
+0.4% +$45.7M 0.16% 100
2024
Q3
$10.8B Buy
23,159,634
+184,113
+0.8% +$88.4M 0.19% 86
2024
Q2
$10.8B Buy
22,975,521
+299,003
+1% +$130M 0.21% 81
2024
Q1
$9.48B Buy
22,676,518
+394,338
+2% +$167M 0.19% 93
2023
Q4
$9.07B Buy
22,282,180
+298,824
+1% +$110M 0.2% 87
2023
Q3
$7.64B Buy
21,983,356
+87,397
+0.4% +$30.6M 0.19% 92
2023
Q2
$7.71B Buy
21,895,959
+49,807
+0.2% +$16.8M 0.18% 92
2023
Q1
$6.88B Buy
21,846,152
+299,249
+1% +$89.8M 0.18% 101
2022
Q4
$6.22B Buy
21,546,903
+414,567
+2% +$126M 0.17% 111
2022
Q3
$6.12B Buy
21,132,336
+293,861
+1% +$84.5M 0.18% 95
2022
Q2
$5.87B Buy
20,838,475
+365,004
+2% +$97.7M 0.17% 106
2022
Q1
$5.34B Buy
20,473,471
+317,629
+2% +$75.4M 0.13% 139
2021
Q4
$4.43B Sell
20,155,842
-286,849
-1% -$55.8M 0.1% 185
2021
Q3
$3.71B Buy
20,442,691
+193,473
+1% +$37.8M 0.09% 205
2021
Q2
$4.08B Sell
20,249,218
-166,493
-0.8% -$34.8M 0.1% 180
2021
Q1
$4.39B Sell
20,415,711
-17,339
-0.1% -$3.81M 0.12% 145
2020
Q4
$4.83B Sell
20,433,050
-256,869
-1% -$58.9M 0.14% 128
2020
Q3
$5.63B Sell
20,689,919
-183,238
-0.9% -$50.6M 0.19% 91
2020
Q2
$6.06B Buy
20,873,157
+264,218
+1% +$71.6M 0.21% 78
2020
Q1
$4.9B Buy
20,608,939
+514,705
+3% +$118M 0.21% 90
2019
Q4
$4.4B Buy
20,094,234
+166,055
+0.8% +$33.6M 0.15% 118
2019
Q3
$3.38B Buy
19,928,179
+266,379
+1% +$47.1M 0.13% 163
2019
Q2
$3.61B Buy
19,661,800
+180,239
+0.9% +$31.5M 0.14% 138
2019
Q1
$3.58B Buy
19,481,561
+92,370
+0.5% +$17.1M 0.14% 131
2018
Q4
$3.21B Buy
19,389,191
+613,939
+3% +$106M 0.14% 129
2018
Q3
$3.62B Buy
18,775,252
+213,550
+1% +$38M 0.14% 127
2018
Q2
$3.15B Buy
18,561,702
+223,136
+1% +$34.6M 0.13% 134
2018
Q1
$2.99B Buy
18,338,566
+404,062
+2% +$66M 0.13% 141
2017
Q4
$2.69B Buy
17,934,504
+322,457
+2% +$47.7M 0.12% 169
2017
Q3
$2.68B Buy
17,612,047
+632,175
+4% +$95.2M 0.13% 154
2017
Q2
$2.19B Buy
16,979,872
+504,982
+3% +$60.8M 0.11% 187
2017
Q1
$1.8B Buy
16,474,890
+560,796
+4% +$49.4M 0.09% 227
2016
Q4
$1.17B Buy
15,914,094
+312,003
+2% +$25.4M 0.07% 338
2016
Q3
$1.36B Buy
15,602,091
+336,916
+2% +$31.8M 0.08% 273
2016
Q2
$1.31B Buy
15,265,175
+329,337
+2% +$28.5M 0.08% 261
2016
Q1
$1.19B Buy
14,935,838
+432,369
+3% +$39.1M 0.08% 280
2015
Q4
$1.82B Buy
14,503,469
+401,421
+3% +$48.5M 0.12% 156
2015
Q3
$1.47B Buy
14,102,048
+256,109
+2% +$32.9M 0.11% 191
2015
Q2
$1.71B Buy
13,845,939
+328,820
+2% +$41.4M 0.12% 171
2015
Q1
$1.59B Sell
13,517,119
-1,984,568
-13% -$238M 0.11% 192
2014
Q4
$1.84B Sell
15,501,687
-1,734,646
-10% -$195M 0.13% 148
2014
Q3
$1.94B Buy
17,236,333
+533,587
+3% +$50.8M 0.15% 130
2014
Q2
$1.58B Buy
16,702,746
+314,096
+2% +$22M 0.12% 160
2014
Q1
$1.16B Buy
16,388,650
+656,739
+4% +$52M 0.1% 216
2013
Q4
$1.17B Buy
15,731,911
+322,023
+2% +$22.4M 0.1% 202
2013
Q3
$1.17B Buy
15,409,888
+3,842,902
+33% +$306M 0.11% 168
2013
Q2
$924M Buy
+11,566,986
New +$852M 0.1% 210

Other funds holding VRTX

Vanguard Group's VRTX Position: Q4 2025 in Review

Vanguard Group reduced its Vertex Pharmaceuticals (VRTX) stake by 0.46% in Q4 2025, selling an estimated $47.9M and leaving 24,105,823 shares worth $10.9B. The position accounts for 0.16% of the portfolio, ranked #103.

Vanguard Group first reported a position in VRTX in Q2 2013 and has held it in 51 quarters since. The position peaked at $11.4B in Q1 2025. 1,670 funds tracked by Wall St. Rank hold VRTX as of Q4 2025.

  • Vanguard Group held 24,105,823 shares of Vertex Pharmaceuticals worth $10.9B as of Q4 2025.
  • Vanguard Group sold 111,042 Vertex Pharmaceuticals shares in Q4 2025, an estimated $47.9M.
  • Vertex Pharmaceuticals made up 0.16% of Vanguard Group's portfolio in Q4 2025, its #103 holding.
  • Vanguard Group first reported a position in Vertex Pharmaceuticals in Q2 2013 and has held it in 51 quarters since.
  • Vanguard Group's Vertex Pharmaceuticals position peaked at $11.4B in Q1 2025.
  • 1,670 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.