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OrbiMed Portfolio holdings

AUM $5.4B
1-Year Est. Return 163.13%
This Fund
S&P 500
This Quarter Est. Return
+12.33%
1 Year Est. Return
+163.13%
3 Year Est. Return
+393.16%
5 Year Est. Return
+486.34%
10 Year Est. Return
+3,312.73%
AUM
$5.23B
AUM Growth
-$160M
Cap. Flow
-$204M
Cap. Flow %
-3.9%
Top 10 Hldgs %
34.65%
Holding
139
New
8
Increased
26
Reduced
20
Closed
24

Top Sells

Rank Stock Value
1
TCDA
Tricida, Inc. Common Stock
TCDA
+$108M
2
ARGX icon
argenx
ARGX
+$94.8M
3
ABBV icon
AbbVie
ABBV
+$80.5M
4
PFE icon
Pfizer
PFE
+$57.8M
5
GH icon
Guardant Health
GH
+$53.4M

Sector Composition

Rank Sector Weight
1 Healthcare 98.41%
2 Miscellaneous 1.59%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
PCVX icon
126
CALL
Vaxcyte
PCVX
$8.74B
-250,000
Closed -$6M
RCUS icon
127
Arcus Biosciences
RCUS
$2.99B
-303,000
Closed -$7.93M
VOR icon
128
Vor Biopharma
VOR
$1.32B
-5,590
Closed -$445K
LENZ
129
LENZ Therapeutics
LENZ
$134M
-121,202
Closed -$2.69M
ACHL
130
DELISTED
Achilles Therapeutics
ACHL
-1,463,251
Closed -$3.31M
SGEN
131
CALL
DELISTED
Seagen Inc. Common Stock
SGEN
-25,000
Closed -$3.42M
JNCE
132
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
-2,928,900
Closed -$6.85M
TCDA
133
DELISTED
Tricida, Inc. Common Stock
TCDA
-10,280,947
Closed -$108M
LOGC
134
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
-8,466,783
Closed -$2.31M
LBPH
135
DELISTED
Longboard Pharmaceuticals, Inc. Common Stock
LBPH
-113,500
Closed -$422K
BHVN
136
DELISTED
Biohaven Pharmaceutical Holding Company Ltd.
BHVN
-170,769
Closed -$25.8M

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OrbiMed's Q4 2022 Portfolio in Review

As of Q4 2022, OrbiMed held 139 positions worth $5.23B, down 3% from $5.39B the previous quarter. Its ten largest holdings account for 35% of the portfolio.

OrbiMed withdrew a net $204M in Q4 2022, closing 24 positions and reducing 20 holdings. Its most notable exit was Tricida, Inc. Common Stock, an estimated $108M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, up from 98% a quarter earlier, followed by Miscellaneous.

Against the trend, OrbiMed opened a new position in Horizon Therapeutics Public Limited Company Ordinary Shares worth $19.5M.

  • OrbiMed's largest Q4 2022 buy was Horizon Therapeutics Public Limited Company Ordinary Shares: 171,000 shares worth $19.5M.
  • OrbiMed added most to Disc Medicine in Q4 2022, an estimated $97.9M increase.
  • OrbiMed's biggest Q4 2022 reduction was argenx, cutting an estimated $94.8M.
  • OrbiMed fully exited Tricida, Inc. Common Stock in Q4 2022, selling an estimated $108M.
  • OrbiMed's ten largest holdings make up 35% of its $5.23B portfolio in Q4 2022.
  • OrbiMed opened 8 new positions and closed 24 in Q4 2022.
  • OrbiMed's portfolio value fell 3% quarter-over-quarter to $5.23B.

Based on OrbiMed's 13F filing for Q4 2022, filed 14 Feb 2023.