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OrbiMed Portfolio holdings

AUM $4.59B
1-Year Est. Return 125.28%
This Fund
S&P 500
This Quarter Est. Return
-4.57%
1 Year Est. Return
+125.28%
3 Year Est. Return
+334.72%
5 Year Est. Return
+344.07%
10 Year Est. Return
+2,748.76%
AUM
$9.86B
AUM Growth
-$803M
Cap. Flow
+$275M
Cap. Flow %
2.79%
Top 10 Hldgs %
30.57%
Holding
177
New
20
Increased
25
Reduced
25
Closed
19

Top Buys

1
XBI icon
State Street SPDR S&P Biotech ETF
XBI
+$123M
2
NPCE icon
Neuropace
NPCE
+$93.1M
3
VECT
VectivBio Holding AG Ordinary Shares
VECT
+$77.8M
4
JANX icon
Janux Therapeutics
JANX
+$77.2M
5
DCPH
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
+$74.2M

Top Sells

1
HAE icon
Haemonetics
HAE
+$94.6M
2
ABCL icon
AbCellera Biologics
ABCL
+$54.5M
3
ADVM
Adverum Biotechnologies
ADVM
+$54.2M
4
MOH icon
Molina Healthcare
MOH
+$38M
5
PAND
Pandion Therapeutics Inc. Common Stock
PAND
+$31.7M

Sector Composition

1 Healthcare 95.36%
2 Technology 0.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GYRE icon
126
Gyre Therapeutics
GYRE
$735M
$9.17M 0.09%
282,480
– –
XFOR icon
127
X4 Pharmaceuticals
XFOR
$367M
$8.93M 0.09%
45,795
– –
WHWK
128
Whitehawk Therapeutics
WHWK
$191M
$8.78M 0.09%
346,263
– –
ASLN
129
DELISTED
ASLAN Pharmaceuticals Limited American Depositary Shares
ASLN
$8.32M 0.08%
63,000
– –
ALXO icon
130
ALX Oncology
ALXO
$269M
$8.2M 0.08%
150,000
– –
STRO icon
131
Sutro Biopharma
STRO
$433M
$8.06M 0.08%
43,370
+8,370
+24% +$1.64M
NRIX icon
132
Nurix Therapeutics
NRIX
$2.46B
$7.96M 0.08%
300,000
– –
GLUE icon
133
Monte Rosa Therapeutics
GLUE
$1.98B
$7.95M 0.08%
+350,000
New +$7.13M
LABP
134
DELISTED
Landos Biopharma, Inc. Common Stock
LABP
$7.87M 0.08%
68,100
– –
DYN icon
135
Dyne Therapeutics
DYN
$3.94B
$7.36M 0.07%
350,000
– –
OTIC
136
DELISTED
Otonomy, Inc.
OTIC
$7.25M 0.07%
3,250,000
– –
NBTX
137
Nanobiotix
NBTX
$2.03B
$6.89M 0.07%
500,000
– –
ACRS icon
138
Aclaris Therapeutics
ACRS
$785M
$6.36M 0.06%
+362,000
New +$8.22M
RXDX
139
DELISTED
Prometheus Biosciences, Inc. Common Stock
RXDX
$6.14M 0.06%
250,000
– –
VERV
140
DELISTED
Verve Therapeutics
VERV
$6.03M 0.06%
+100,000
New +$4.15M
LUNG icon
141
Pulmonx
LUNG
$61.7M
$5.51M 0.06%
125,000
– –
SBBP
142
DELISTED
Strongbridge Biopharma plc.
SBBP
$5.18M 0.05%
1,744,669
– –
OBIO icon
143
Orchestra BioMed
OBIO
$219M
$5.1M 0.05%
500,000
– –
OGN icon
144
Organon & Co
OGN
$3.54B
$5.05M 0.05%
+166,939
New +$5.5M
SRPT icon
145
Sarepta Therapeutics
SRPT
$1.83B
$5.03M 0.05%
64,700
-135,578
-68% -$10.3M
TARA icon
146
Protara Therapeutics
TARA
$232M
$4.38M 0.04%
450,000
– –
ADAG
147
Adagene
ADAG
$241M
$3.73M 0.04%
275,000
– –
TRML
148
DELISTED
Tourmaline Bio
TRML
$3.63M 0.04%
+24,724
New +$3.79M
INZY
149
DELISTED
Inozyme Pharma
INZY
$3.22M 0.03%
+188,704
New +$3.28M
IFRX icon
150
InflaRx
IFRX
$298M
$3.16M 0.03%
1,064,118
– –
3 4 5
6
7

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