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OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+6.96%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$7.91B
AUM Growth
+$7.91B
Cap. Flow
+$959M
Cap. Flow %
12.12%
Top 10 Hldgs %
33.78%
Holding
159
New
26
Increased
22
Reduced
25
Closed
17

Top Buys

1
PRLD icon
Prelude Therapeutics
PRLD
$470M
2
PMVP icon
PMV Pharmaceuticals
PMVP
$260M
3
AFIB
Acutus Medical, Inc. Common Stock
AFIB
$163M
4
ACET icon
Adicet Bio
ACET
$71.6M
5
CALC icon
CalciMedica
CALC
$56.9M

Top Sells

1
ASND icon
Ascendis Pharma
ASND
$128M
2
CI icon
Cigna
CI
$82.5M
3
NTRA icon
Natera
NTRA
$81.6M
4
GKOS icon
Glaukos
GKOS
$46.5M
5
ALEC icon
Alector
ALEC
$34.2M

Sector Composition

1 Healthcare 98.49%
2 Financials 0.64%
3 Technology 0.57%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ARNA
126
DELISTED
Arena Pharmaceuticals Inc
ARNA
$4.99M 0.06%
66,700
– –
ACAD icon
127
Acadia Pharmaceuticals
ACAD
$4.34B
$4.41M 0.06%
+107,000
New +$4.41M
SYBX icon
128
Synlogic
SYBX
$17.4M
$4.1M 0.05%
2,029,996
– –
KYMR icon
129
Kymera Therapeutics
KYMR
$3.1B
$3.23M 0.04%
+100,000
New +$3.23M
OBSV
130
DELISTED
ObsEva SA Ordinary Shares
OBSV
$3.23M 0.04%
1,303,000
-1,302,531
-50% -$3.23M
IFRX icon
131
InflaRx
IFRX
$117M
$2.89M 0.04%
678,525
– –
MIST icon
132
Milestone Pharmaceuticals
MIST
$151M
$2.82M 0.04%
+385,791
New +$2.82M
ANAB icon
133
AnaptysBio
ANAB
$630M
$2.66M 0.03%
180,442
-195,358
-52% -$2.88M
RNA icon
134
Avidity Biosciences
RNA
$6.12B
$1.8M 0.02%
63,860
-136,140
-68% -$3.83M
PPBT
135
Purple Biotech
PPBT
$3.76M
$1.53M 0.02%
346,197
-3,115,786
-90% –
CRIS icon
136
Curis
CRIS
$21.5M
$1.45M 0.02%
1,241,494
– –
NBRV
137
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$1.41M 0.02%
2,644,600
-2,000,000
-43% -$1.07M
BMY.RT
138
DELISTED
Bristol-Myers Squibb Company Contingent Value Rights
BMY.RT
$900K 0.01%
400,000
+50,000
+14% +$113K
CALT
139
DELISTED
Calliditas Therapeutics AB American Depositary Shares
CALT
$425K 0.01%
17,696
-207,304
-92% -$4.98M
BLRX
140
BioLineRX
BLRX
$15.5M
$114K ﹤0.01%
69,240
– –
GNMK
141
DELISTED
GenMark Diagnostics, Inc
GNMK
– –
-732,000
Closed -$10.8M
VYNE icon
142
VYNE Therapeutics
VYNE
$8.09M
– –
-593,883
Closed -$1.03M
TXG icon
143
10x Genomics
TXG
$1.66B
– –
-92,700
Closed -$8.28M
SLQT icon
144
SelectQuote
SLQT
$366M
– –
-1,255,000
Closed -$31.8M
REGN icon
145
Regeneron Pharmaceuticals
REGN
$59.8B
– –
-30,900
Closed -$19.3M
RCUS icon
146
Arcus Biosciences
RCUS
$1.24B
– –
-220,350
Closed -$5.45M
PFE icon
147
Pfizer
PFE
$141B
– –
0
– –
NTLA icon
148
Intellia Therapeutics
NTLA
$1.26B
– –
-137,100
Closed -$2.88M
INSP icon
149
Inspire Medical Systems
INSP
$2.53B
– –
-347,000
Closed -$30.2M
IMVT icon
150
Immunovant
IMVT
$2.91B
– –
-354,575
Closed -$8.63M
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