O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+33.09%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$7.07B
AUM Growth
+$7.07B
Cap. Flow
-$90.9M
Cap. Flow %
-1.29%
Top 10 Hldgs %
31.27%
Holding
162
New
21
Increased
29
Reduced
28
Closed
28

Top Buys

1
BNR
Burning Rock Biotech
BNR
$128M
2
RPTX icon
Repare Therapeutics
RPTX
$106M
3
ORIC icon
Oric Pharmaceuticals
ORIC
$98.6M
4
BIIB icon
Biogen
BIIB
$63M
5
KROS icon
Keros Therapeutics
KROS
$63M

Top Sells

1
ASND icon
Ascendis Pharma
ASND
$255M
2
GILD icon
Gilead Sciences
GILD
$98.4M
3
PFE icon
Pfizer
PFE
$98.3M
4
HCA icon
HCA Healthcare
HCA
$63.8M
5
SYK icon
Stryker
SYK
$61.8M

Sector Composition

1 Healthcare 97.61%
2 Financials 1.61%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
CRIS icon
126
Curis
CRIS
$21.5M
$1.5M 0.02%
1,241,494
-116,869
-9% -$141K
ELDN icon
127
Eledon Pharmaceuticals
ELDN
$155M
$1.46M 0.02%
3,183,314
– –
BMY.RT
128
DELISTED
Bristol-Myers Squibb Company Contingent Value Rights
BMY.RT
$1.25M 0.02%
350,000
– –
VYNE icon
129
VYNE Therapeutics
VYNE
$8.09M
$1.03M 0.01%
593,883
-1,157,412
-66% -$2M
ARVN icon
130
Arvinas
ARVN
$580M
$986K 0.01%
29,400
-965,600
-97% -$32.4M
BLRX
131
BioLineRX
BLRX
$15.5M
$118K ﹤0.01%
69,240
– –
PFNX
132
DELISTED
Pfenex Inc.
PFNX
– –
-1,305,034
Closed -$11.5M
XENT
133
DELISTED
Intersect ENT, Inc
XENT
– –
-68,553
Closed -$812K
OTIC
134
DELISTED
Otonomy, Inc.
OTIC
– –
-71,994
Closed -$142K
AGRX
135
DELISTED
Agile Therapeutics, Inc
AGRX
– –
-1,200,000
Closed -$2.23M
APTX
136
DELISTED
Aptinyx Inc. Common Stock
APTX
– –
-1,162,108
Closed -$2.51M
NBSE
137
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
– –
-371,114
Closed -$2.64M
TVRD
138
Tvardi Therapeutics, Inc. Common Stock
TVRD
$270M
– –
-592,800
Closed -$7.83M
ZLAB icon
139
Zai Lab
ZLAB
$3.48B
– –
-254,000
Closed -$13.1M
XLV icon
140
Health Care Select Sector SPDR Fund
XLV
$33.8B
– –
-113,200
Closed -$10M
XBI icon
141
SPDR S&P Biotech ETF
XBI
$5.29B
– –
-127,200
Closed -$9.85M
PTCT icon
142
PTC Therapeutics
PTCT
$4.41B
– –
-1,148,723
Closed -$51.2M
PFE icon
143
Pfizer
PFE
$141B
– –
-3,012,100
Closed -$98.3M
NGNE icon
144
Neurogene
NGNE
$284M
– –
-921,800
Closed -$10.5M
MBIO icon
145
Mustang Bio
MBIO
$11.1M
– –
-251,685
Closed -$675K
KALV icon
146
KalVista Pharmaceuticals
KALV
$713M
– –
-420,641
Closed -$3.22M
HCA icon
147
HCA Healthcare
HCA
$95.4B
– –
-709,800
Closed -$63.8M
CRBP icon
148
Corbus Pharmaceuticals
CRBP
$121M
– –
0
– –
BTAI icon
149
BioXcel Therapeutics
BTAI
$52.7M
– –
-107,300
Closed -$2.4M
BMRN icon
150
BioMarin Pharmaceuticals
BMRN
$11.3B
– –
-540,500
Closed -$45.7M
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