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OrbiMed Portfolio holdings

AUM $5.05B
1-Year Est. Return 125.28%
This Fund
S&P 500
This Quarter Est. Return
+2.21%
1 Year Est. Return
+125.28%
3 Year Est. Return
+334.72%
5 Year Est. Return
+344.07%
10 Year Est. Return
+2,748.76%
AUM
$5.06B
AUM Growth
-$395M
Cap. Flow
-$256M
Cap. Flow %
-5.05%
Top 10 Hldgs %
43.96%
Holding
127
New
13
Increased
22
Reduced
22
Closed
13

Top Buys

Rank Stock Value
1
ITGR icon
Integer Holdings
ITGR
+$40.8M
2
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$39.5M
3
EXAS
Exact Sciences
EXAS
+$29.3M
4
ARGX icon
argenx
ARGX
+$22M
5
AMGN icon
Amgen
AMGN
+$21M

Top Sells

Rank Stock Value
1
ALPN
Alpine Immune Sciences Inc
ALPN
+$106M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$104M
3
JANX icon
Janux Therapeutics
JANX
+$60.8M
4
ESPR
Esperion Therapeutics
ESPR
+$36.7M
5
SRRK icon
Scholar Rock
SRRK
+$30.6M

Sector Composition

Rank Sector Weight
1 Healthcare 98.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TGTX icon
101
TG Therapeutics
TGTX
$8.21B
$2.37M 0.05%
+133,200
New +$2.13M
BMRN icon
102
BioMarin Pharmaceuticals
BMRN
$11.9B
$2.15M 0.04%
26,100
-1,252,400
-98% -$104M
CMMB
103
Chemomab Therapeutics
CMMB
$11.4M
$2.05M 0.04%
560,318
-1
-0% -$3
ORIC icon
104
Oric Pharmaceuticals
ORIC
$1.17B
$2.03M 0.04%
287,100
– –
NXTC icon
105
NextCure
NXTC
$21.4M
$1.81M 0.04%
95,100
– –
APLM icon
106
Apollomics
APLM
$39.5M
$1.81M 0.04%
85,655
– –
VIGL
107
DELISTED
Vigil Neuroscience
VIGL
$1.8M 0.04%
448,891
– –
DVAX
108
DELISTED
Dynavax Technologies
DVAX
$1.27M 0.03%
113,500
– –
KZR
109
DELISTED
Kezar Life Sciences
KZR
$1.16M 0.02%
192,700
– –
LSB
110
DELISTED
LakeShore Biopharma
LSB
$910K 0.02%
140,428
-13,015
-8% -$106K
TRAW icon
111
Traws Pharma
TRAW
$7.39M
$467K 0.01%
+41,810
New +$674K
XERS icon
112
Xeris Biopharma Holdings
XERS
$1.45B
$181K ﹤0.01%
80,420
– –
OMIC
113
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$152K ﹤0.01%
18,023
– –
APLS
114
CALL
DELISTED
Apellis Pharmaceuticals
APLS
– –
-150,000
Closed -$8.82M
ARWR icon
115
Arrowhead Research
ARWR
$12B
– –
-739,651
Closed -$21.2M
JBIO
116
Jade Biosciences
JBIO
$1.17B
– –
-16,154
Closed -$16.7M
BOLT icon
117
Bolt Biotherapeutics
BOLT
$7.4M
– –
-77,050
Closed -$2.16M
CALC icon
118
CalciMedica
CALC
$12M
– –
-297,380
Closed -$1.24M
CTMX icon
119
CytomX Therapeutics
CTMX
$690M
– –
-3,544,578
Closed -$7.73M
ESPR
120
DELISTED
Esperion Therapeutics
ESPR
– –
-13,708,731
Closed -$36.7M
PRAX icon
121
Praxis Precision Medicines
PRAX
$8.16B
– –
-460,512
Closed -$28.1M
TXG icon
122
10x Genomics
TXG
$5.9B
– –
-225,200
Closed -$8.45M
VTYX
123
DELISTED
Ventyx Biosciences
VTYX
– –
-1,870,456
Closed -$10.3M
ALPN
124
DELISTED
Alpine Immune Sciences Inc
ALPN
– –
-2,680,496
Closed -$106M
AFIB
125
DELISTED
Acutus Medical Inc
AFIB
– –
-2,648,386
Closed -$498K
2 3 4
5
6

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HSA
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NL
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BPWM
Badgley Phelps Wealth Managers Seattle, Washington $5.02B AUM 21.87% 1-Year Est. Return
LFG
Lazard Frères Gestion Paris, France $5.07B AUM 20.66% 1-Year Est. Return
JIM
Jensen Investment Management Lake Oswego, Oregon $5.07B AUM 4.98% 1-Year Est. Return
CTC
Central Trust Company Jefferson City, Missouri $5.08B AUM 25.65% 1-Year Est. Return
PAMP
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SGM
Skye Global Management West Palm Beach, Florida $5B AUM 11.9% 1-Year Est. Return

OrbiMed's Q2 2024 Portfolio in Review

As of Q2 2024, OrbiMed held 127 positions worth $5.06B, down 7.2% from $5.46B the previous quarter. Its ten largest holdings account for 44% of the portfolio.

OrbiMed withdrew a net $256M in Q2 2024, closing 13 positions and reducing 22 holdings. Its most notable exit was Alpine Immune Sciences Inc, an estimated $106M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, down from 99% a quarter earlier.

Against the trend, OrbiMed opened a new position in Integer Holdings worth $40.4M.

  • OrbiMed's largest Q2 2024 buy was Integer Holdings: 349,221 shares worth $40.4M.
  • OrbiMed added most to Exact Sciences in Q2 2024, an estimated $29.3M increase.
  • OrbiMed's biggest Q2 2024 reduction was BioMarin Pharmaceuticals, cutting an estimated $104M.
  • OrbiMed fully exited Alpine Immune Sciences Inc in Q2 2024, selling an estimated $106M.
  • OrbiMed's ten largest holdings make up 44% of its $5.06B portfolio in Q2 2024.
  • OrbiMed opened 13 new positions and closed 13 in Q2 2024.
  • OrbiMed's portfolio value fell 7.2% quarter-over-quarter to $5.06B.

Based on OrbiMed's 13F filing for Q2 2024, filed 14 Aug 2024.