O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+2.19%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$5.03B
AUM Growth
+$5.03B
Cap. Flow
-$321M
Cap. Flow %
-6.38%
Top 10 Hldgs %
44.26%
Holding
122
New
8
Increased
22
Reduced
23
Closed
12

Top Buys

1
ALNY icon
Alnylam Pharmaceuticals
ALNY
$60.8M
2
ITGR icon
Integer Holdings
ITGR
$40.4M
3
ARGX icon
argenx
ARGX
$24.7M
4
EXAS icon
Exact Sciences
EXAS
$22.5M
5
AMGN icon
Amgen
AMGN
$22.3M

Top Sells

1
ALPN
Alpine Immune Sciences, Inc. Common Stock
ALPN
$106M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
$103M
3
JANX icon
Janux Therapeutics
JANX
$54.3M
4
ESPR icon
Esperion Therapeutics
ESPR
$36.7M
5
PRAX icon
Praxis Precision Medicines
PRAX
$28.1M

Sector Composition

1 Healthcare 99.36%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
VIGL
101
DELISTED
Vigil Neuroscience
VIGL
$1.8M 0.04%
448,891
– –
DVAX icon
102
Dynavax Technologies
DVAX
$1.19B
$1.27M 0.03%
113,500
– –
KZR icon
103
Kezar Life Sciences
KZR
$28.5M
$1.16M 0.02%
1,927,000
– –
LSB
104
LakeShore Biopharma
LSB
$34.9M
$910K 0.02%
1,404,280
-130,150
-8% -$84.3K
TRAW icon
105
Traws Pharma
TRAW
$11.4M
$467K 0.01%
+1,045,261
New +$467K
XERS icon
106
Xeris Biopharma Holdings
XERS
$1.27B
$181K ﹤0.01%
80,420
– –
OMIC
107
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$152K ﹤0.01%
18,023
-522,674
-97% –
KNTE
108
DELISTED
Kinnate Biopharma Inc. Common Stock
KNTE
– –
-8,009,729
Closed -$21.3M
AFIB
109
DELISTED
Acutus Medical, Inc. Common Stock
AFIB
– –
-2,648,386
Closed -$498K
ALPN
110
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
– –
-2,680,496
Closed -$106M
SOLV icon
111
Solventum
SOLV
$12.4B
– –
0
– –
VTYX icon
112
Ventyx Biosciences
VTYX
$184M
– –
-1,870,456
Closed -$10.3M
TXG icon
113
10x Genomics
TXG
$1.66B
– –
-225,200
Closed -$8.45M
PRAX icon
114
Praxis Precision Medicines
PRAX
$980M
– –
-460,512
Closed -$28.1M
PFE icon
115
Pfizer
PFE
$141B
– –
0
– –
ESPR icon
116
Esperion Therapeutics
ESPR
$490M
– –
-13,708,731
Closed -$36.7M
CTMX icon
117
CytomX Therapeutics
CTMX
$350M
– –
-3,544,578
Closed -$7.73M
CALC icon
118
CalciMedica
CALC
$45M
– –
-297,380
Closed -$1.24M
BOLT icon
119
Bolt Biotherapeutics
BOLT
$9.29M
– –
-1,541,000
Closed -$2.16M
JBIO
120
Jade Biosciences, Inc. Common Stock
JBIO
$245M
– –
-565,374
Closed -$16.7M
ARWR icon
121
Arrowhead Research
ARWR
$3.84B
– –
-739,651
Closed -$21.2M
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