O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+30.47%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$5.45B
AUM Growth
+$5.45B
Cap. Flow
-$287M
Cap. Flow %
-5.27%
Top 10 Hldgs %
39.03%
Holding
130
New
20
Increased
22
Reduced
29
Closed
17

Top Buys

1
AVBP icon
ArriVent BioPharma
AVBP
$54.1M
2
CYTK icon
Cytokinetics
CYTK
$47.9M
3
GERN icon
Geron
GERN
$40.9M
4
QTTB icon
Q32 Bio
QTTB
$38.4M
5
ESPR icon
Esperion Therapeutics
ESPR
$36.7M

Top Sells

1
RYZB
RayzeBio, Inc. Common Stock
RYZB
$147M
2
GRCL
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$93.5M
3
UTHR icon
United Therapeutics
UTHR
$84.9M
4
SWTX
SpringWorks Therapeutics
SWTX
$74.4M
5
THRX
Theseus Pharmaceuticals, Inc. Common Stock
THRX
$71.7M

Sector Composition

1 Healthcare 99.34%
2 Industrials 0%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
PHGE icon
101
BiomX
PHGE
$14.3M
$2.03M 0.04% 4,517,589 – –
CMMB
102
Chemomab Therapeutics
CMMB
$16.3M
$1.75M 0.03% 2,241,274 – –
KZR icon
103
Kezar Life Sciences
KZR
$28.9M
$1.74M 0.03% 1,927,000 – –
VIGL
104
DELISTED
Vigil Neuroscience
VIGL
$1.53M 0.03% 448,891 – –
DVAX icon
105
Dynavax Technologies
DVAX
$1.19B
$1.41M 0.03% +113,500 New +$1.41M
CALC icon
106
CalciMedica
CALC
$37.7M
$1.24M 0.02% 297,380 – –
LSB
107
LakeShore Biopharma
LSB
$33M
$1.1M 0.02% 1,534,430 -1,701,881 -53% -$1.23M
AFIB
108
DELISTED
Acutus Medical, Inc. Common Stock
AFIB
$498K 0.01% 2,648,386 – –
LYEL icon
109
Lyell Immunopharma
LYEL
$213M
$445K 0.01% +199,500 New +$445K
OMIC
110
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$278K 0.01% 540,697 – –
XERS icon
111
Xeris Biopharma Holdings
XERS
$1.26B
$178K ﹤0.01% +80,420 New +$178K
AGIO icon
112
Agios Pharmaceuticals
AGIO
$2.19B
– – -45,000 Closed -$1M
ALNY icon
113
Alnylam Pharmaceuticals
ALNY
$58.5B
– – -79,400 Closed -$15.2M
CLDX icon
114
Celldex Therapeutics
CLDX
$1.47B
– – -58,800 Closed -$2.33M
GILD icon
115
Gilead Sciences
GILD
$140B
– – -100,000 Closed -$8.1M
HUM icon
116
Humana
HUM
$36.5B
– – -109,900 Closed -$50.3M
ILMN icon
117
Illumina
ILMN
$15.8B
– – -30,300 Closed -$4.22M
IOVA icon
118
Iovance Biotherapeutics
IOVA
$807M
– – -4,707,458 Closed -$38.3M
PFE icon
119
Pfizer
PFE
$141B
– – 0 – –
QURE icon
120
uniQure
QURE
$896M
– – -1,347,900 Closed -$9.13M
RAPT icon
121
RAPT Therapeutics
RAPT
$188M
– – -281,413 Closed -$6.99M
RCUS icon
122
Arcus Biosciences
RCUS
$1.13B
– – -117,000 Closed -$2.23M
UTHR icon
123
United Therapeutics
UTHR
$13.8B
– – -386,100 Closed -$84.9M
RCM
124
DELISTED
R1 RCM Inc. Common Stock
RCM
– – -4,803,200 Closed -$50.8M
FUSN
125
DELISTED
Fusion Pharmaceuticals Inc. Common Shares
FUSN
– – -3,122,770 Closed -$30M
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5
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