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OrbiMed Portfolio holdings

AUM $5.4B
1-Year Est. Return 163.13%
This Fund
S&P 500
This Quarter Est. Return
+55.76%
1 Year Est. Return
+163.13%
3 Year Est. Return
+393.16%
5 Year Est. Return
+486.34%
10 Year Est. Return
+3,312.73%
AUM
$7B
AUM Growth
+$1.73B
Cap. Flow
-$5.41M
Cap. Flow %
-0.08%
Top 10 Hldgs %
37.61%
Holding
156
New
40
Increased
17
Reduced
34
Closed
20

Sector Composition

Rank Sector Weight
1 Healthcare 97.81%
2 Financials 1.53%
3 Miscellaneous 0.66%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
ATRC icon
101
AtriCure
ATRC
$2.86B
$5.48M 0.08%
+168,621
New +$4.8M
AMRN
102
Amarin Corp
AMRN
$294M
$5.35M 0.08%
12,480
+1,425
+13% +$541K
PSNL icon
103
Personalis
PSNL
$1.72B
$5.27M 0.08%
483,842
SYBX
104
DELISTED
Synlogic
SYBX
$5.24M 0.07%
135,333
INCY icon
105
Incyte
INCY
$24.7B
$5.2M 0.07%
+59,500
New +$5.08M
ARNA
106
DELISTED
Arena Pharmaceuticals Inc
ARNA
$5M 0.07%
110,000
ACAD icon
107
Acadia Pharmaceuticals
ACAD
$4.61B
$4.11M 0.06%
96,143
NTLA icon
108
Intellia Therapeutics
NTLA
$1.59B
$3.85M 0.05%
262,100
-65,500
-20% -$911K
DERM
109
CALL
DELISTED
Dermira, Inc.
DERM
$3.79M 0.05%
+250,000
New +$2.16M
AZN icon
110
AstraZeneca
AZN
$251B
$3.47M 0.05%
+34,800
New +$3.28M
SNY icon
111
Sanofi
SNY
$102B
$3.43M 0.05%
+68,400
New +$3.2M
WHWK
112
Whitehawk Therapeutics
WHWK
$233M
$3.24M 0.05%
346,263
BMRN icon
113
BioMarin Pharmaceuticals
BMRN
$12.5B
$2.93M 0.04%
+34,700
New +$2.62M
KALV
114
DELISTED
KalVista Pharmaceuticals
KALV
$2.86M 0.04%
160,541
+121,808
+314% +$1.59M
ICPT
115
DELISTED
Intercept Pharmaceuticals, Inc.
ICPT
$2.83M 0.04%
22,800
-9,400
-29% -$842K
FLXN
116
DELISTED
Flexion Therapeutics, Inc.
FLXN
$2.75M 0.04%
+133,000
New +$2.24M
CRIS icon
117
Curis
CRIS
$2.74M
$2.31M 0.03%
3,396
+292
+9% +$212K
MYOK
118
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$2.03M 0.03%
27,900
-755,132
-96% -$45.8M
SNDX icon
119
Syndax Pharmaceuticals
SNDX
$1.62B
$1.86M 0.03%
212,000
ELDN icon
120
Eledon Pharmaceuticals
ELDN
$220M
$1.85M 0.03%
176,851
MIRM icon
121
Mirum Pharmaceuticals
MIRM
$6.1B
$1.75M 0.03%
+71,300
New +$760K
ADAP
122
DELISTED
Adaptimmune Therapeutics
ADAP
$1.62M 0.02%
1,350,655
IMGN
123
DELISTED
Immunogen Inc
IMGN
$1.46M 0.02%
+286,800
New +$973K
INSM icon
124
Insmed
INSM
$26.2B
$1.41M 0.02%
59,000
-503,300
-90% -$10.2M
PTGX icon
125
Protagonist Therapeutics
PTGX
$9.28B
$1.35M 0.02%
+191,209
New +$1.9M

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OrbiMed's Q4 2019 Portfolio in Review

As of Q4 2019, OrbiMed held 156 positions worth $7B, up 33% from $5.27B the previous quarter. Its ten largest holdings account for 38% of the portfolio.

OrbiMed's Q4 2019 filing shows 40 new, 17 increased, 34 reduced and 20 closed positions. Its largest new stake was 89bio: 4,004,442 shares worth $105M. The largest sale was Avedro, Inc Common Stock, an estimated $96.3M.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, up from 98% a quarter earlier, followed by Financials and Miscellaneous.

  • OrbiMed's largest Q4 2019 buy was 89bio: 4,004,442 shares worth $105M.
  • OrbiMed added most to Mirati Therapeutics, Inc. Common Stock in Q4 2019, an estimated $77.7M increase.
  • OrbiMed's biggest Q4 2019 reduction was Neurocrine Biosciences, cutting an estimated $66.9M.
  • OrbiMed fully exited Avedro, Inc Common Stock in Q4 2019, selling an estimated $96.3M.
  • OrbiMed's ten largest holdings make up 38% of its $7B portfolio in Q4 2019.
  • OrbiMed opened 40 new positions and closed 20 in Q4 2019.
  • OrbiMed's portfolio value rose 33% quarter-over-quarter to $7B.

Based on OrbiMed's 13F filing for Q4 2019, filed 14 Feb 2020.