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OrbiMed Portfolio holdings

AUM $5.05B
1-Year Est. Return 125.28%
This Fund
S&P 500
This Quarter Est. Return
+9.78%
1 Year Est. Return
+125.28%
3 Year Est. Return
+334.72%
5 Year Est. Return
+344.07%
10 Year Est. Return
+2,748.76%
AUM
$8.3B
AUM Growth
-$82M
Cap. Flow
-$615M
Cap. Flow %
-7.41%
Top 10 Hldgs %
34.19%
Holding
170
New
23
Increased
24
Reduced
50
Closed
20

Sector Composition

Rank Sector Weight
1 Healthcare 94.81%
2 Financials 0.79%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
CHRS icon
76
Coherus Oncology
CHRS
$222M
$28.4M 0.34%
1,722,400
+241,918
+16% +$4.29M
GILD icon
77
Gilead Sciences
GILD
$167B
$28.2M 0.34%
364,600
RNAC icon
78
Cartesian Therapeutics
RNAC
$225M
$26.3M 0.32%
56,427
-5,000
-8% -$2.01M
VRCA icon
79
Verrica Pharmaceuticals
VRCA
$92.8M
$24M 0.29%
147,973
SYK icon
80
Stryker
SYK
$133B
$23.1M 0.28%
130,200
-13,200
-9% -$2.25M
CRSP icon
81
CRISPR Therapeutics
CRSP
$4.68B
$22M 0.27%
496,200
SVA
82
DELISTED
Sinovac Biotech, Ltd
SVA
$21.6M 0.26%
2,839,500
NVTA
83
DELISTED
Invitae Corporation
NVTA
$21.3M 0.26%
1,274,549
-243,648
-16% -$2.77M
FOLD
84
DELISTED
Amicus Therapeutics
FOLD
$21.3M 0.26%
1,763,277
-5,309,223
-75% -$74.2M
NTLA icon
85
Intellia Therapeutics
NTLA
$1.52B
$21.3M 0.26%
744,600
-131,400
-15% -$3.82M
ALPN
86
DELISTED
Alpine Immune Sciences Inc
ALPN
$20.9M 0.25%
3,298,516
SYRE icon
87
Spyre Therapeutics
SYRE
$8.68B
$20.7M 0.25%
86,621
+12,000
+16% +$2.8M
SCPH
88
DELISTED
scPharmaceuticals
SCPH
$20M 0.24%
3,409,865
AET
89
DELISTED
Aetna Inc
AET
$19.9M 0.24%
+98,200
New +$19.2M
VRTX icon
90
CALL
Vertex Pharmaceuticals
VRTX
$124B
$19.3M 0.23%
100,000
-75,000
-43% -$13.4M
RCKT icon
91
Rocket Pharmaceuticals
RCKT
$343M
$19.1M 0.23%
775,000
SEM
92
DELISTED
Select Medical
SEM
$19M 0.23%
1,920,424
-7,497,291
-80% -$77.6M
NBIX icon
93
Neurocrine Biosciences
NBIX
$18.4B
$16.9M 0.2%
137,800
NTRA icon
94
Natera
NTRA
$36.1B
$16.4M 0.2%
684,086
-300,000
-30% -$7.25M
WHWK
95
Whitehawk Therapeutics
WHWK
$182M
$16M 0.19%
346,263
VRNA
96
DELISTED
Verona Pharma
VRNA
$15.6M 0.19%
1,250,396
NVO
97
Novo Nordisk
NVO
$225B
$15.6M 0.19%
660,000
DBVT
98
DBV Technologies
DBVT
$799M
$14.9M 0.18%
66,520
+25,450
+62% +$5.17M
IMGN
99
DELISTED
Immunogen Inc
IMGN
$13.9M 0.17%
1,469,189
-1,435,081
-49% -$13.8M
PVLA
100
Palvella Therapeutics
PVLA
$2.05B
$13.8M 0.17%
30,699
-8,551
-22% -$3.72M

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OrbiMed's Q3 2018 Portfolio in Review

As of Q3 2018, OrbiMed held 170 positions worth $8.3B, down 0.98% from $8.38B the previous quarter. Its ten largest holdings account for 34% of the portfolio.

OrbiMed withdrew a net $615M in Q3 2018, closing 20 positions and reducing 50 holdings. Its most notable exit was Alnylam Pharmaceuticals, an estimated $125M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 95% of assets, up from 94% a quarter earlier, followed by Financials.

Against the trend, OrbiMed opened a new position in Principia Biopharma Inc. Common Stock worth $76.1M.

  • OrbiMed's largest Q3 2018 buy was Principia Biopharma Inc. Common Stock: 2,605,713 shares worth $76.1M.
  • OrbiMed added most to Humana in Q3 2018, an estimated $104M increase.
  • OrbiMed's biggest Q3 2018 reduction was Biogen, cutting an estimated $88.7M.
  • OrbiMed fully exited Alnylam Pharmaceuticals in Q3 2018, selling an estimated $125M.
  • OrbiMed's ten largest holdings make up 34% of its $8.3B portfolio in Q3 2018.
  • OrbiMed opened 23 new positions and closed 20 in Q3 2018.
  • OrbiMed's portfolio value fell 0.98% quarter-over-quarter to $8.3B.

Based on OrbiMed's 13F filing for Q3 2018, filed 14 Nov 2018.