O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
-2.08%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$10.7B
AUM Growth
+$10.7B
Cap. Flow
+$450M
Cap. Flow %
4.22%
Top 10 Hldgs %
33.33%
Holding
184
New
34
Increased
39
Reduced
24
Closed
28

Top Buys

1
EWTX icon
Edgewise Therapeutics
EWTX
$453M
2
GRCL
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$121M
3
HAE icon
Haemonetics
HAE
$94.6M
4
TERN icon
Terns Pharmaceuticals
TERN
$83.4M
5
IMA
ImageneBio, Inc. Common Stock
IMA
$82.9M

Top Sells

1
PRVL
Prevail Therapeutics Inc. Common Stock
PRVL
$319M
2
PRLD icon
Prelude Therapeutics
PRLD
$241M
3
PFE icon
Pfizer
PFE
$133M
4
BIIB icon
Biogen
BIIB
$125M
5
CNC icon
Centene
CNC
$120M

Sector Composition

1 Healthcare 95.15%
2 Technology 0.12%
3 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
MREO
51
Mereo BioPharma
MREO
$275M
– –
0
– -$49.5M
ORIC icon
52
Oric Pharmaceuticals
ORIC
$1.03B
$57.3M 0.54%
2,337,574
-584,393
-20% -$14.3M
DBTX
53
DELISTED
Decibel Therapeutics, Inc. Common Stock
DBTX
$56.2M 0.53%
+4,945,192
New +$56.2M
ADVM icon
54
Adverum Biotechnologies
ADVM
$68.2M
$54.2M 0.51%
5,501,144
– –
OSH
55
DELISTED
Oak Street Health, Inc.
OSH
$52.5M 0.49%
967,000
+518,900
+116% +$28.2M
BNR
56
Burning Rock Biotech
BNR
$85.6M
$51.1M 0.48%
1,897,663
-2,264,012
-54% -$60.9M
TCDA
57
DELISTED
Tricida, Inc. Common Stock
TCDA
$50.9M 0.48%
9,614,280
– –
TMO icon
58
Thermo Fisher Scientific
TMO
$183B
$50.3M 0.47%
110,300
– –
ARCT icon
59
Arcturus Therapeutics
ARCT
$467M
$49.8M 0.47%
1,206,886
-73,200
-6% -$3.02M
CRIS icon
60
Curis
CRIS
$21.5M
$49.4M 0.46%
4,366,494
– –
APTO
61
DELISTED
Aptose Biosciences, Inc.
APTO
$48M 0.45%
8,030,000
– –
HARP
62
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$47.8M 0.45%
2,285,704
+450,000
+25% +$9.41M
CGEM icon
63
Cullinan Oncology
CGEM
$456M
$47.8M 0.45%
+1,146,145
New +$47.8M
VRNA
64
Verona Pharma
VRNA
$9.18B
$47.6M 0.45%
5,694,841
– –
TELA icon
65
TELA Bio
TELA
$65.4M
$45.1M 0.42%
3,027,542
– –
XENE icon
66
Xenon Pharmaceuticals
XENE
$2.99B
$44.7M 0.42%
2,497,917
– –
APLT icon
67
Applied Therapeutics
APLT
$73.7M
$42.3M 0.4%
2,257,387
+485,556
+27% +$9.11M
CRNX icon
68
Crinetics Pharmaceuticals
CRNX
$3.26B
$42.1M 0.39%
2,753,567
– –
SIBN icon
69
SI-BONE Inc
SIBN
$700M
$41.5M 0.39%
1,305,300
-63,200
-5% -$2.01M
NSTG
70
DELISTED
NanoString Technologies, Inc.
NSTG
$40.9M 0.38%
622,900
-1,004,000
-62% -$66M
MOH icon
71
Molina Healthcare
MOH
$9.6B
$38M 0.36%
162,400
– –
KALA icon
72
KALA BIO
KALA
$105M
$36.8M 0.34%
5,465,030
– –
VOR icon
73
Vor Biopharma
VOR
$253M
$35.9M 0.34%
+833,333
New +$35.9M
FUSN
74
DELISTED
Fusion Pharmaceuticals Inc. Common Shares
FUSN
$34.6M 0.32%
3,224,770
– –
TRIL
75
DELISTED
Trillium Therapeutics Inc.
TRIL
$34M 0.32%
3,165,200
+205,000
+7% +$2.2M
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3
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